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Accuneb

Accuneb is used to prevent and treat difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness caused by lung diseases such as asthma and chronic obstructive pulmonary disease.

Other names for this medication:
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Also known as: Albuterol

Description

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. It is also used to prevent bronchospasm caused by exercise.

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Accuneb. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose. Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine. Connect the nebulizer to the face mask or mouthpiece. Use the face mask or mouthpiece to breathe in the medicine. Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone. Clean all the parts of the nebulizer after each use.

The albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) and albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) are used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly.

To use the inhalation aerosol:

The inhaler should be at room temperature before you use it. Insert the metal canister firmly and fully into the actuator. This actuator should not be used with other inhaled medicines. Remove the cap and look at the mouthpiece to make sure it is clean. Point the inhaler away from your face. Shake the inhaler well and test spray it in the air 3 times for ProAir® HFA or 4 times for Proventil® HFA before using it for the first time or if the inhaler has not been used for more than 2 weeks. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright. Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister. Hold your breath for about 10 seconds, then breathe out slowly. If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler. When you have finished all of your doses, rinse your mouth with water and spit the water out. Clean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and air dry it completely. If you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose. After using the inhaler, wash the mouthpiece again and dry it completely. If the mouthpiece becomes blocked, washing it will help. The Proventil® HFA inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The counter will turn red when there are only 20 doses left, to remind you to refill your prescription.

To use the inhalation powder:

Take the inhaler from the foil pouch before you use it for the first time. The inhaler provides about 200 inhalations. The dose counter will change to red when there are "20" doses left. Call your doctor or pharmacist for a refill of prescription or medicine. Make sure the cap is closed before using this medicine. Do not open the cap unless you are going to use it. Hold the inhaler upright as you open the cap fully until you hear a "click". Your inhaler is now ready to use. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it. Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not block the vent above the mouthpiece with your lips or fingers. Hold your breath for about 10 seconds or as long as you comfortably can. Remove the inhaler from your mouth and check the dose counter to make sure you received the medicine. Close the cap firmly over the mouthpiece after using the inhaler. Always close the cap after each use. If you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully. Do not use a spacer or volume holding chamber together with the ProAir® Digihaler™. Keep the inhaler clean and dry at all times. Do not wash or put any part of the inhaler in water. Replace the ProAir® Digihaler™ if it has been washed or placed in water. If you need to clean the mouthpiece, wipe it gently with a dry cloth or tissue.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation aerosol dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation powder dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation solution dosage form (used with a nebulizer): For prevention of bronchospasm: Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed. Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed. Children younger than 2 years of age—Use and dose must be determined by your child's doctor.

Overdose

If you overdose Accuneb and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store unopened vials of this medicine at room temperature, away from heat and direct light. Do not freeze. An open vial of medicine must be used right away.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store Proventil® HFA inhaler with the mouthpiece down.

Throw away the ProAir® Digihaler™ or ProAir® Respiclick® 13 months after opening the foil pouch, when the dose counter reaches "0", or after the expiration date, whichever comes first.

Detailed Accuneb dosage information

Side effects

The most common side effects associated with Accuneb are:

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Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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A single ie1 transcript of 2.5 kb was detected at 1 h p.i., peaking at 8 h p.i. However, no significant improvement in tumor size, number of lymph nodes, or staging is found. Relation of structure to biaxin medicine the bacteriostatic activity of sulfonamides. CH (4 wk at 0.5 atm) and control rats were renal denervated and instrumented for the measurement of renal blood flow (RBF) and blood pressure. Our findings suggest that Rab membrane targeting is dictated by a complex mechanism involving GEFs, GAPs, effectors, and C-terminal interaction with membranes to varying extents, and possibly other binding partners.

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Furthermore, leptin receptor protein, as determined by immunocytochemistry, was colocalized in virtually all vasopressin and oxytocin cells in the supraoptic nucleus. Pleomorphic adenocarcinoma of the pancreas with extrapancreatic proliferation. The remarkable stability of chimeric, sialic acid-derived alpha/delta-peptides in human blood plasma. We recently demonstrated that extracellular nucleotides, and particularly UTP, induced migration of cultured arterial smooth muscle cells (ASMCs). The patient was found to be free of gastrointestinal bleeding on 6 month follow-up. Osteolytic rims around the staple limbs within the lunate occurred in all wrists. Child abuse is a complex phenomenon characterized by maladaptive behaviors between children and their parents.

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Effects of phytohemagglutinin on humoral antibody response, delayed hypersensitivity, and homograft rejection. We also found that the vascular deficits are improved via antioxidant modulation of the endothelial nitric oxide synthase, an enzyme primarily responsible for the production of nitric oxide, while neuronal deficits are improved via modulation of the phosphorylation status of the protein tau, which is a neuronal cytoskeletal stabilizer. The effects of Cepharanthin on the recovery of hematopoietic stem cells after X-ray irradiation. The Arrhenius curves were found to have an inflection point at 42.0-43.0 degrees C in vivo and 41.5-42.5 degrees C in vitro. With gas chromatography-negative chemical ionization mass spectrometry, only mercapturic acid metabolites arising from 25 micrograms doses and higher could be quantified because of interference from endogenous compounds. Epinephrine effect on glycogen phosphorylase activity in catfish liver and muscles.

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Idiopathic acute fatty liver of pregnancy associated with transient diabetes insipidus. Replication of a premenstrual decrease in right-ear advantage on language-related dichotic listening tests of cerebral laterality. The morphology of the lesion and the fact that the max dose of cardizem iv primary tubercular complex, at pulmonary level, was masked by a simultaneous candidiasis infection were probably due to cell-mediated immunodeficiency consequent to the ulcerative colitis and on-going therapy (Salazopyrin and prednisone). Plant peroxisomes participate in various metabolic processes, some of which are co-operated by peroxisomes and other organelles, such as mitochondria and chloroplasts. Papillophlebitis associated with coexisting factor V Leiden and prothrombin G20210A mutations.

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