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Accupain (Tramadol)

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Accupain is used for the management of pain in adults. Although it's a little weaker than other opioids, it can still be addictive and habit-forming. Accupain is available as both an immediate-acting tablet and an extended-release tablet.

Other names for this medication:
Anatram, Arrestadol, Atdol, Avdol, Cemadol, Combitram, Contradoc, Cradol, Damol, Decotram, Dolex, Domadol, Formador, Medol, Nomadol, Nosdol, Novadol, Ondol, Opiran, Ospidol, Ramax, Ramcet, Relidol, Rybix, Supridol, Taxidol, Tolydol, Traiz, Tramabit, Tramache, Tramacip, Tramak, Tramex, Tramol, Tranat, Transic, Trazac, Tremtec, Tryme, Victadol, Xidol

Similar Products:
Zantac, Avelox, Flomax, Allegra, Urispas, Starlix, Zyvox, Aristocort, Cardicon, Furocot, Tramazol, Vominorm, Lisoretic,

Also known as: Tramadol


Accupain ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Accupain ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Accupain ER.

Never share Accupain ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Accupain ER.

Accupain ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Accupain ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Accupain ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Accupain ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Accupain ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Tablets should not be removed from the blisters until right before use. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Accupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Accupain ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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In traditional hierarchical models of information processing, visual representations feed into conceptual systems, but conceptual categories do not exert an influence on visual processing. Synthesis of a non-viral vector for gene transfer via the high-affinity neurotensin receptor. No specific tracer to identify the pathophysiological process of aneurysmal dilatation is yet available, however. Similarly the antigonadotrophic effects of afternoon injections of melatonin, 5-methoxytryptophol and arginine vasotocin could be partially destroyed by 100 micrograms and completely abolished by 1 mg melatonin administered in the morning. The group of hybrid implants was not statistically evaluated due to a small size of the subgroup. Particularly strong dependences of the use of benefits have been found in the specialist care, for consultations rendered due to a disease (not prevention) and at the territorial (provincial) level--not at the level of integrated occupational health service authorities. The accumulation, metabolism and biological effects of astatine in rats and monkeys. Clinical feasibility and applicability of the CSPS were further evaluated by a group of general nurses who used case vignette approach in CSPS risk assessment in clinical settings.

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Anti-Angiogenic Drugs in the Treatment of Metastatic Renal Cell Carcinoma: Advances in Clinical Application. Post-cardiac arrest patients have high fluid requirements during therapeutic hypothermia, probably due to increased extravasation. In patients with bronchial asthma a raised LPO level was noted in parallel with a decrease in alpha-tocopherol content and SOD activity up to the values below the normal ones. These findings may help us understand the molecular mechanism of miR-27a in the tumorigenesis of osteosarcoma and may provide new diagnostic and therapeutic options for the treatment of this neoplasia. It is concluded that both drugs can be given concomitantly without any dosage adjustment of theophylline. Bilateral fracture-dislocation of the sacroiliac joint: a case report.

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In fact, in interphase cells colchicine was comparatively more effective than thiabendazole in promoting depolymerization of cytoplasmic microtubules. Evolution is generally favorable with topical antifungal treatment. Right ventricular uptake score, as assessed by modified tomographic imaging, and regional RV count relative to peak left ventricular (LV) count (RV/LV count ratio) were compared with RV regional and global function. While pyrophosphate and citrate were detected with high sensitivity, fluoride and perchlorate produced no response. Neuroendoscopic third ventriculostomy in a patient with occluded foramen of Monro: a case report. Here we describe the molecular and physiological characterization of two further alleles (gai-t5, gai-t7) identified during the Ds mutagenesis experiment. Many researchers have speculated that mimicry is related to activity in the human mirror system (HMS), a network of parietofrontal regions that are involved in both action execution and observation. Effect of pulsed electromagnetic field (PEMF) on infarct size and inflammation after cerebral ischemia in mice.

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Gradual delay in glucose-induced first phase insulin secretion by the pancreatic islets of 7 week-, 6 month-, and 1 year-old rats. To evaluate the long-term effects of trabeculectomy on the progression of visual field damage in patients with progressive normal-tension glaucoma (NTG). We used data from the 1985, 1993, 1994, 1997, and 1998 National Ambulatory Medical Care Surveys, which is a nationally representative series of surveys of office-based practice employing clustered sampling. From this study it is concluded that FCM clearly contributes to the recognition of subgroups of patients with different prognosis. MR imaging findings in medullary pilocytic astrocytomas consist generally of focal or diffuse cord-enlarging masses that are irregularly shaped, accompanied by cystic elements and hydromyelia, present different degrees of contrast enhancement, high water diffusivity and a propensity for the thoracic and cervical cord. Levels of the H3K4me3 activation mark correlate inversely with H3K27me3 levels at MAF4 and MAF5 loci. ADVANCES IN ANGIOGRAPHY IN RELATION TO THE PROBLEM OF CEREBROVASCULAR DISEASE. In the hope that some varieties of the post-phlebitic syndrome might be treated by implanting a preserved vein valve, studies have been made of the mechanical properties of vein valves and vein wall before and after preservation with glutaraldehyde.

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The hexamer molecular dynamics trajectories have been used to test the restrained parameter crystallographic refinement model for nucleic acids. To determine the burden of hospitalised, radiologically confirmed pneumonia (World Health Organization protocol) in Northern Territory Indigenous children. Of the 23 infected neonates, 15 presented with early sepsis and/or pneumonia and nine had conjunctivitis. On the bactericidal properties of Dioxane with regard to the plague microbe. The WR of MIBG during exercise may be an independent prediction variable, with a clinical relevance different from that of the WR at rest. Importance and current status of geriatric departments in general hospitals.

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Diagnosis of mitral and aortic stenosis by the method of catheterization of the left cavity of the heart and aortia. Blunted heart rate response as a predictor of cardiac death in patients undergoing vasodilator stress technetium-99m sestamibi gated SPECT myocardial perfusion imaging. As those prerequisits are not provided everywhere, medical care of those newborns effected in qualified centers is to be recommended. The latest hyperbaric chambers are lightweight, portable and easy to operate. No such effect was observed after treatment of the cells with phorbol 12-myristate 13-acetate or retinoic acid, two other inducers of differentiation in these cells. These residues are part of a C-terminal 3(10)-helix and provide contacts with the rest of the protein or its ligands. Correlation with clinical indicators of delirium suggests pathophysiological significance. Morphometric estimation of regional differences in the dog lung.

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Acute oculogyric crisis after administration of prochlorperazine. In this epoch, the advantages of protein chemical synthesis will complement recombinant-DNA methods, and will be used to provide rapid access to small proteins or functional receptor domains. Focal retardation and arrestment of growth of bones due to vitamin A intoxication. The wet and dry weights and the nitrogen, collagen, calcium, phosphorus, and DNA contents of the calluses showed no correlation with the radiographic size of the calluses. Anterior spinal fusion as an important adjunct in the treatment of tuberculosis of the spine. Injection of buprenorphine and buprenorphine/naloxone tablets in Malaysia. Study of trace element correlations with drought tolerance in different sorghum genotypes using energy-dispersive X-ray fluorescence technique.

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Pharmacokinetics in children: history, considerations, and applications. The isoform type of gamma subunits of GABA(A) receptor is a molecular determinant of its pharmacological characteristics. There was a significant correlation between one measure of what is zetia generic brain metabolism (PCr/PI) and the neurobehavioral assessment rating for infants with IVH. Incidence and predictors of readmission to the cardiac surgery intensive care unit: A retrospective cohort study in Greece. A simple manipulator for inserting microelectrodes into the brains of the freely moving rat. Recent observations on intercurrent relations between the teeth and sex. The results of this study support the need for early and long term intervention with ICS, even in patients with relatively mild asthma.

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One hundred and sixty-six consecutive patients (221 knees) who underwent navigation-assisted TKA and were followed for a minimum of 2 years were included. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. In addition, lipid species have been suggested to play a role in lipotoxicity and as signaling molecules during adipose tissue inflammation. In the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study of 2,164 patients with clinically stable COPD, 337 smokers with normal lung function, and 245 never-smokers, we measured a large number of clinical parameters, lung function, exercise tolerance, biomarkers, and amount of emphysema by computed tomography. The analysis showed that nursing professionalism is determined by three attributes of cognitive, attitudinal, and psychomotor. Multidrug resistance in animal cells is defined as the simultaneous resistance to a variety of compounds which appear to be structurally and mechanistically unrelated. This investigation studies the effect of the shot-blasting treatment on the cyclic deformation behavior of a commercially pure titanium, with two microstructures: equiaxed and acicular. To directly investigate the importance of SHP-1 to phagocytic cell function, bone marrow neutrophils were isolated from both me/me and me(v)/me(v) mice and examined with respect to their responses to various stimuli. Outward signs are abrupt and repeated interruptions in the flow of conversation or actions while subjective experience is that of a total and uncontrollable emptying of the mind.

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Fifty patients with biopsy-proved unresectable primary or metastatic cancer to the liver were treated. These regional wall motion impairments are parallel to the reduced global left ventricular function. Knowledge of signaling mechanisms has increased dramatically during the past decade, particularly in the areas of development, biochemical signaling cascades, synaptic transmission and ion channel biophysics. Synthetic nucleoside mimics are important candidates in the searing for antiviral and anticancer drugs allegra m tablet uses in english . All consecutive patients reconstructed with intercalary (whole-circumference) allografts after tumor resection in the long bones during 1989 to 2009 were evaluated. As many as 185 adolescents with hypotensive type vegetovascular dysfunction who ranged between 11 to 14 years old were studied for impact of a conventional treatment and that involving the use of hyperbaric oxygenation on the blood content of prostaglandins E2 and F2 alpha.

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These are the main reasons which prompted EULAR (European League against Rheumatism) to publish recommendations mainly for the management of the main musculoskeletal conditions seen in daily practice. This proves the entropic origin for the bending stiffness, which is of order kT. The EGFP-positive cells generated in the VZ in the control slices exhibited a multipolar morphology, but within several hours they became bipolar (with a leading process and an axon-like process) and migrated toward the pial surface. These data allowed to determine the position of the strain A/Leningrad/385/80 HA gene regarding to the evolutionary relationships of HA genes of influenza A (H3N2 subtype) viruses. We have constructed a cavity-dumped dye laser optimized for use with kHz repetition rate ultrafast lasers for performing experiments on atomic and molecular systems. Numerous natural compounds have a potential for therapeutic applications, but may have to be chemically modified to alter toxic side effects.

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