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Acivir (Acyclovir)
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Acivir

Acivir is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection.

Other names for this medication:
Accrivir, Acivir, Acloriv, Aclovir, Acvirall, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Acylab, Alovir, Cevirin, Civir, Cloviderm, Clovir, Clovirax, Clyvir, Cutivir, Cycloex, Cyclopiz, Docvir, Herperax, Herzovir, Lovir, Lyrovir, Nisivir, Okavir, Optiviral, Oveer, Psyvir, Ridoherp, Rivol, Rowapil, Setuvir, Spaclovir, Virex, Virucid, Zoylex

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Also known as: Acyclovir

Description

Acivir (acyclovir) is an antiviral drug. Acyclovir slows the growth and spread of the herpes virus in the body.

Acivir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox.

Acivir will not cure herpes, but it can lessen the symptoms of the infection.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Agitation, confusion, dizziness, and drowsiness may be especially likely to occur in elderly patients who are usually more sensitive than younger adults to the central nervous system effects of acyclovir.

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Radiation from the furnace was found to propagate in the fiber as an attenuating mode at temperatures above 800 degrees C. The convergence rate of the POCS algorithm (projection onto convex sets) used for image reconstruction from spectral phase is defined and analyzed, and the characteristics of images optimally reconstructed from phase-only information are presented. Quality criteria for content validity, internal consistency, criterion validity, construct validity, reproducibility, longitudinal validity, responsiveness, floor and ceiling effects, and interpretability were derived from existing guidelines and consensus within our research group. Bretons in Paris: regional ties and urban networks in an age of urbanization. Composition of the patients was studied by the social groups, educational level, marital status and housing conditions.

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Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis. GRK3-silenced control cells displayed altered CXCR4 attenuation and enhanced chemotaxis, as did WHIM(WT) cells. Mechanisms by which a phorbol ester and a diacylglycerol analog inhibit hen granulosa cell steroidogenesis. This reaction is important in transferring activated acetyl groups to the mitochondria and in regulating the acetyl-CoA/CoA pools within the cell. These in vitro-infected cell line responses were compared to IL-8 production from in vitro C. Immediately after isolation, monocytes were analyzed for MHC class II antigen expression using a radiolabelled monoclonal antibody specific for a monomorphic determinant on HLA-DR antigens. aeruginosa bacteremia due to isolates with reduced piperacillin-tazobactam susceptibility, empirical piperacillin-tazobactam therapy was associated with increased mortality. Lobation of integuments is not an atavism indicating evolution from telomes, but simply a morphogenetic constraint from the necessity of closure of the micropyle.

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This work, along with the HVL data from approximately 200 functioning x-ray tubes used for all applications that were monitored for more than 8 years, indicated there is no significant increase in HVL with diagnostic x-ray tube use. Investigation of the venous hemodynamics of the lower limb by venous pressure models. Larger trials with adequate power to detect clinically important benefits are required. Effect of physical training in humans on the response of isolated fat cells to epinephrine. The ethanolic extract of PGE has significant anti-inflammatory activity. Atypical maturation of pSTS suggests altered trajectories for functional segregation and integration of networks in ASD, potentially related to impaired cognitive and sensorimotor development. The selection of patients for community reprovision during the first three years of an active closure programme at two large mental hospitals in the North East Thames Regional Health Authority was studied. Progressive systemic sclerosis: radionuclide esophageal scintigraphy and manometry. Ultramicroscopic analysis revealed that UVA1 treatment decreased the diameter of the broad collagen fibrils, mainly in the upper reticular layer. Of these, three (two with oral cavity tumors and one with an oropharynx tumor) had clinically positive node in level I.

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The RNA is located on the inner surface of the decameric complex near the top end. The absorption of ingested neptunium, plutonium and americium in newborn hamsters. CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. Effects of an alpha-glucosidase inhibitor, acarbose, on blood glucose and serum lipids in streptozotocin-induced diabetic rats. A method for maintaining, in vitro, TV-monitoring and counting ciliary beat frequency of samples from human ciliated respiratory epithelium brushing. Here, by analysing previously published data from HIV-1 reverse transcriptase in vitro assays, we show a trade-off between enzymatic accuracy and the maximum rate of polymerization, thus providing a biochemical basis for the fitness cost of fidelity in HIV-1. Psychiatric assessment of survey respondents was based on the Diagnostic Interview Schedule, which also provided self-report information about violent behavior. Massage therapy protocol for post-anterior cruciate ligament reconstruction patellofemoral pain syndrome: a case report. Tools for spatial conservation planning are aimed to conserve biodiversity, often in the context of a limited budget.

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Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing. Anti-KCA-3, a monoclonal antibody reactive with a rat complement C3 receptor, distinguishes Kupffer cells from other macrophages. A consecutive cohort of patients who had Austin-Moore hemiarthroplasties performed at our district general hospital between August 2000 and July 2004 were included in the study. Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activities. At early times, viral RNA was detected only in the trigeminal and olfactory nerves and in their immediate connections in all mice. Furthermore, comprehensive studies are presented on the number of hemopoietic progenitors and precursors, as well as of other cell types, in YS, L, and blood at precisely sequential stages in embryos and early fetuses (i.e., at 4.5-8 wk and 9-10 wk postconception, respectively).

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However, this review will address the structure and nature of the protein produced in cells from MPS patients, the biological activity of this protein, and the incorporation of the protein into, and location within, subcellular fractions. New paradigm for treating recurrent depression: from symptom control to managing enduring vulnerabilities. Many hypotheses have been advanced to explain its etiology: viral inflammation, vascular diseases, allergic reaction, rupture of intralabyrinthine membranes, and autoimmune diseases. Further, a close correspondence was observed in the distribution of labeled neurons obtained by the two histochemical procedures in the midbrain and pontine tegmentum, including the laterodorsal tegmental nucleus, some areas in the caudal pontine and bulbar reticular formation, and the central gray of the closed medulla oblongata. Analysis and design of optical systems by use of sensitivity analysis of skew ray tracing. In conclusion, developmental changes of brain activation during mental rotation are leading to a bilateral parietal activation pattern and faster performance. The detection of methamphetamine in the presence of nicotine has been successfully accomplished using in situ chemical derivatization with propyl chloroformate as the derivatization reagent and ion mobility spectrometry (IMS).

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A pressure analysis of the role of these structures in the formation and maintenance of the axopodia of Actinosphaerium nucleofilum (Barrett). Because human narcolepsy is thought to be multigenic, the canine narcolepsy-MHC dissociation suggests that the dog model may help elucidate the non-MHC narcolepsy gene(s). Recently, the Spine Trauma Study Group published a proposal for a standardized set of measurement techniques for the radiographic evaluation of subaxial cervical spine trauma. CAVPE seems to offer better responses and disease-free survival in this non-selected group of low and intermediate lymphoma patients. Investigation of dynamic spectral characteristics of water in blood plasma hydrosols from breast cancer patients. This can you drink alcohol when taking phenergan was evidenced by the demonstration of RSV-infected cells without any syncytia formation in the monolayers treated with RSV antibody-positive serum.

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Permanent preoperative carotid artery occlusion and carotid body tumor surgery. Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes. Osmotic demyelination syndrome has been reported in patients with end-stage renal disease, but the specific MRI findings in this patient group have not been documented in detail. Hybridization analysis using a cloned beta-lysin determinant (hlb) and cloned attP-containing DNA fragments as probes demonstrated that beta-lysin conversion mediated by the triple-converting phages and phage phi 13 was caused by insertional inactivation of the chromosomally encoded hlb determinant by orientation-specific integration of phage DNA following lysogenization. Glutathione reductase activity was little affected by age when expressed as activity per lens, per gram lens or per mg soluble protein, indicating that activity of this enzyme did not increase with lens size as would a representative lenticular protein. A patient is herein presented who arrived at the emergency department 6 hours after onset of classic signs of acute arterial occlusion. As questions and techniques evolve in the field of neuroscience, advances in PRV tracing will certainly follow. Lupulon and humulon, their antibacterial effects and therapeutic use in tuberculous infections. Starting from the experience of my gastroentheriologists colleagues, presented in previous papers, we insist on minim invasive therapeutical gestures. An increase in the expression of HLA-Dr antigen and transferrin receptors was greater when cells were incubated with 13-cRA than with either BC, CTX, or RBG, while carotenoids produced a greater increase in the expression of IL-2 receptors than 13-cRA.

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