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Acupain (Tramadol)
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Acupain

Acupain is a strong painkiller used to treat moderate to severe pain. It is generally used when non-opioid painkillers don't work as well to control the pain anymore. Acupain may cause drowsiness. You shouldn't drive or use heavy machinery or perform dangerous activities until you know how this drug affects you.

Other names for this medication:
Anazac, Antram, Armadol, Arodol, Avdol, Axedol, Bludol, Bramadol, Cadol, Cemadol, Cosdol, Damol, Didol, Doleira, Dolomed, Dolstar, Domaspas, Ibudol, Jpdol, Meridol, Mobiya, Neutram, Nopidol, Opidol, Pacadon, Relidol, Tolydol, Tradol, Tramacip, Tramafen, Tramazol, Tramdop, Tranat, Trandy, Trasic, Tridol, Tromar, Ubitdol, Ultracon, Urgendol, Urogendo, Xidol, Zotadol, Zytram

Similar Products:
Norvasc, Plaquenil, Revia, Soma, Zudena, Arava, Levaquin, Ritosin, Metazol, Hyperchol, Caverject, Pironex,

Also known as: Tramadol

Description

Acupain ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Acupain: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Acupain is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Acupain dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Acupain dosage information

Side effects

The most common side effects associated with Acupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Acupain if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Acupain should not be given to a child younger than 12 years old. Acupain ER should not be given to anyone younger than 18 years old.

Do not give Acupain to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Acupain. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Acupain is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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5-10-year follow-up of 12 patients with childhood-onset cerebral X-linked adrenoleukodystrophy shows the long-term beneficial effect of bone marrow transplantation when the procedure is done at an early stage of the disease. A rare neoplasm of the reticulo-endothelial system: reticulohistiocytoma of the epididymis. In addition, careful skeletal and muscular reconstruction of the surgical defect is necessary for a successful outcome. An efficient solid-phase strategy for the construction of chemokines. Spontaneous transitional cell carcinoma in the urinary bladder of a strain 13 guinea pig.

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Enhanced replication of HIV-1 in vivo in pigtailed macaques (Macaca nemestrina). Subjects were required to complete a 20-question cognitive examination and a ten-point satisfaction inventory. Response of cultured rat liver epithelial cell lines to tumour-promoting phorbol esters. Study of 2 cases of adenoma and reticulosarcoma of the umbilicus. In addition heterocellular gap junctional contacts were detected between oocytes and presumptive granulosa cells as early as fetal day 17, indicating that the potential for direct intercellular communication between granulosa cells and oocytes is established from the earliest contact. We describe a child with familial hypocalciuric hypercalcemia (FHH) in whom the hypercalcemia seemed to interfere with tissue healing after tympanoplasty. Symptoms in skin prick test-negative subjects were associated with personal and parental smoking habit. Diagnosis of cystic fibrosis in the kindred of an infant with CFTR-related metabolic syndrome: importance of follow-up that includes monitoring sweat chloride concentrations over time. The Wartenberg Pendulum Test has been devised for measuring spasticity at the knee, but has been shown to be unsuitable for measuring more severe spasticity. The effects of congenital tumours on their hosts were often considerable: death by generalization (malignant lymphomas), ascites (mesotheliomas) or the growth of large abdominal tumours (nephroblastomas, mixed tumours).

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In patients with a ruptured aneurysm, however, the C3-F gene frequency was significantly increased in subjects aged 40-49 years followed by a marked and statistically significant decline with increasing age. The Markov model is second order to accommodate an extended memory range including the previous as well as the next-to-previous time instant. The advantages in demonstrating this unusual set of circumstances by computerized tomography are discussed. The LQoLP allows suggestions for specific improvements in mental health care for long-term psychiatric patients. Histidine-2-oxoglutarate aminotransferase activity in Salmonella typhimurium. The aim of this review is to construct a detailed account of the role of the district nurse (generalist registered nurse providing nursing care in primarily home settings) in providing palliative care, to determine if and how district nursing care provides effective care to such patients at home, and to examine the utility of a realist review for the above purpose. We were able to continue to follow ninety-nine of these patients for an average of 8.1 years (range, five to 12.5 years). All patients presented with nasolacrimal duct obstruction and underwent an endoscopic dacryocycstorhinostomy utilizing a 9 mm endonasal ballon. In some cognitively delayed children who require a vagal nerve stimulator for treatment of their seizures, there is a risk of wound breakdown and infection from obsessive tampering with the wound. Craniofacial surgery has evolved through an era of refinement and finesse, both in techniques and in results.

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Preventing traumatic complications in convulsive shock therapy by curare by A. Differential effects of kainic-acid-induced hippocampal lesions on the acquisition of the jump-box avoidance task in mice. Cryptorchid testes were biopsied at three, five and eight months and all were excised at 12 months. A similar diurnal variation in pulmonary artery diastolic pressure was seen in the groups--that is, values were low during the day and higher at night, with the maximum values between midnight and 6 am. Photochemical reduction of CO2 with ascorbate in aqueous solution using vesicles acting as photocatalysts. Previous reports have suggested that atrioventricular (AV) flow disturbances accompanying atrial myxomas mimic mitral stenosis.

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Lung transplant recipients are at risk of numerous complications, which range from early events, such as primary graft dysfunction, to late events, including opportunistic infection or graft loss caused by chronic rejection. HMG-D protein could bind to the wide minor groove of the A-form TAR RNA. Stage classification of chronic lymphatic leukemia as a basis for therapy decisions. We hypothesized that part of the non-specific antidiarrhoeal effect of octreotide is mediated by a proabsorptive or antisecretory effect on small intestinal active electrolyte transport. While the former is independent of the pressure in the liquids, the latter two are pressure dependent and are enhanced when the pressure difference across the membrane is increased. In vitro studies have shown that zinc inhibits the activity of the proapoptotic enzyme caspase-3. TH activity is inhibited by peroxynitrite (ONOO(-)) by a mechanism that involves nitration of tyrosine residues and oxidation of cysteine residues in the enzyme. In this model, the intercalation occurs on the ethynyl side of the BTD, and as a consequence, the PhOMe portion is free to perform the ICT process with the BTD core and stabilizes it in the excited state. Establishment and metabolic analysis of a model microbial community for understanding trophic and electron accepting interactions of subsurface anaerobic environments. BHT is inhibitory only at very high concentrations, and BHA tends to increase ethylene formation.

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The increasing relevance of 3D methods in orthodontic diagnostics and treatment planning calls for the development of new analysis methods and the definition of three-dimensional mean values. Prenatal radiation-induced limb defects mediated by Trp53-dependent apoptosis in mice. The structure of a short fragment of the human HIV-1 membrane glycoprotein gp41 has been examined using a combination of parallel tempering molecular dynamics (PTMD) and far UV circular dichroism spectroscopy. Music reduces panic: an initial study of listening to preferred music improves male patient discomfort and anxiety during flexible cystoscopy. Here, we show that Rad17, a replication checkpoint protein, is required for the early recruitment of the MRN complex to the DSB site that is independent of MDC1 and contributes to ATM activation. Discriminating between true-positive and false-positive clinical mastitis alerts from automatic milking systems. The same applied for those PD patients with high vascular risk, in whom the cerebral circulation could be restored. Following deglycosylation of purified ASGP-R, we detected the H2b and H2c proteins in HepG2 and HuH-7 hepatoma cells, using an antibody directed against a COOH-terminal peptide common to all H2 isoforms (anti-H2-COOH) and another antibody against a 19-amino acid cytoplasmic insert found only in H2b (anti-H2-Cyto19). It was concluded that the antitussive action of both caramiphen and dextromethorphan is due to a selective effect on the cough center in the brainstem of the cat.

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