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Adaret (Adapalene)

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Adaret is used to treat acne. Adaret is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin. Adaret has the unique ability to inhibit keratinocyte differentiation and decrease keratin deposition.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Xenical, Ultram, Pamelor, Avodart, Mircette, Pepcid, Alzorix, Zeriphyllin, Eridium, Tramadol, Xanef, Hapsen,

Also known as: Adapalene


Adaret is a third-generation topical retinoid primarily used in the treatment of acne. Adaret is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adaret gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adaret works under the skin surface to unclog pores and clear up pimples. Adaret is also known as Adapalene, Adapen, Adaferin. Generic name of Adaret is Adapalene.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


If you overdose Adaret and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adaret are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid exposure to sunlight or tanning beds. Adaret can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in topical acne medications or skin cleansers).

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

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Double-labeling experiments demonstrated the coexistence of decorin and collagen IX in some fibrils of intermediate diameter, although most fibril fragments from adult cartilage were strongly positive for one component and lacked the other. Assess the willingness of dentists in Jordan to treat HIV-infected patients. Comparison of three in-house multiplex PCR assays for the detection of Neisseria gonorrhoeae and Chlamydia trachomatis using real-time and conventional detection methodologies. Complication rates were compared with those in a similar group of age-matched patients who were left aphakic at the time of surgery. HABP1 low-expression resulted in an increased five-year OS and PFS. Additional lipoblast-like cells can be occasionally identified among mature adipocytes. Although regarded as a member of the carbonic anhydrase gene family, the encoded protein (CAR8) has no reported enzymatic activity. We consider that the motile stage could correspond to the stage in vivo when astrocyte precursor cells migrate from the ventricular and subventricular regions to take up position in different parts of the developing brain. Inhibition resulted from treatments that lowered the pH, and stimulation resulted from an increase in cell biomass (based on plate counts) and from a different process whereby rates of transformation per bacterial cell rapidly increased as much as 10-fold. Questions about quitting (Q2): design and methods of a Multiphase Optimization Strategy (MOST) randomized screening experiment for an online, motivational smoking cessation intervention.

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Efforts to further evaluate and translate the variation measure to the clinical setting are warranted. Applying known techniques to convey this information proves hard and sometimes even impossible. The aim of this study was to investigate the clinicopathological characteristics of GATA binding protein 3 (GATA3)-positive breast cancers as well as the association of GATA3 expression with response to chemotherapy. In ovarian cancers, PRL-3 expression correlates with disease progression, being higher in advanced (stage III) than in early (stage I) tumors. Using gramicidin as a model system, we have explained its observed conversion from stretch-activated to stretch-inactivated gating as a function of bilayer thickness and composition.

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There are three technical possibilities: bifurcated graft, scarf graft, bypass with interfemoral graft. For scientists, it is not easy to explain the etiology and pathophysiology of these eating disorders. Isotonic solutions of NaCl, glucose or sucrose were ineffective. Because of compatibility with healthcare trends, program philosophy, and university functions, one baccalaureate program chose to organize curricular content using the structure of the practice-based Omaha System. These findings suggest a central role for TatC-type proteins in the translocation of tightly folded proteins across a spectrum of biological membranes. The present study also shows a good correlation between the concentrations of hexachlorobenzene (HCB) and pentachloroanisol (PCA) in fish for the first time. Optical coherence tomography (OCT), fluorescein angiography, electrophysiologic testing, visual field, magnetic resonance imaging, and mutation screening of PTCH gene. The aim of this study was to clarify whether anastomosis-related complications and local recurrence influenced the rate of permanent stomas in a long-term follow-up.

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The rate of Glycyl-Proline influx as compared to those of amino acid influxes suggests the occurrence of a carrier-mediated transport process for this dipeptide in the rat intestine as previously shown in the rabbit. Comparisons with the molluscan shell are drawn and a rationale for the architecture suggested. Public health nursing: a crisis in definition, role, and function. Canadian Cardiovascular Congress 2001 and 54th annual meeting of the Canadian Cardiovascular Society. Re: Thyroid iodine content measured by x-ray fluorescence in amiodarone-induced thyrotoxicosis. Based on these data we further aimed to investigate the role of CD97 small isoform in gastric cancer progression in vivo by employing the cells with a stable CD97 small isoform knock-down and an orthotopic gastric cancer mouse model.

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Following pollination, the upper and lower floret pistils fuse, producing a connated kernel with two genetically distinct embryos and the endosperms fused along their abgerminal face. Consequently, monocytes and their progeny can phenotypically mimic EPCs in various experimental models. Msx2 has an inhibitory effect, whereas Six3 does not affect the Sox2 promoter. Characterization and distribution of undersulfated chondroitin sulfate and chondroitin in leptocephalous larvae of elopomorph fishes. Findings were correlated to skeletal maturity, and frequencies were compared with adult data. Due to their functional properties, these proteins are principally of industrial interest.

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Radical neck dissections were performed in 39 necks and modified radical neck dissections were performed in 8 necks. Based on the recent high-resolution laboratory experiments on propagating shear rupture, the constitutive law that governs shear rupture processes is discussed in view of the physical principles and constraints, and a specific constitutive law is proposed for shear rupture. These results do not support the hypothesis that high intake of flavonols and flavones reduces the development of type 2 diabetes, although we cannot rule out a modest inverse association with intake of apples and tea. Our 8-station Objective Structured Clinical Exam is described in detail. Myofibrillar protein degradation and muscle proteinases in normal and diabetic rats. Examination of AKAP12 promoter methylation in skin cancer using methylation-sensitive high-resolution melting analysis.

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Autoantibodies to the 27 C-terminal amino acids of calpastatin are detected in a restricted set of connective tissue diseases and may be useful for diagnosis of rheumatoid arthritis in community cases of very early arthritis. Successful moxifloxacin prophylaxis against experimental streptococcal aortic valve endocarditis. In this study, the accumulation and fractionation of REEs in wheat (Triticum aestivum L.) were investigated using solution culture with exogenous mixed REEs. Specificity of therapeutic drug monitoring of tacrolimus in kidney transplant patients. Antimicrobial activity and biodiversity of endophytic fungi in Dendrobium devonianum and Dendrobium thyrsiflorum from Vietnam. Irregularities in configuration of the hairs, longitudinal grooving and areas of bifurcation and re-adhesion of the hair shafts are demonstrated. Objective functions of online weight noise injection training algorithms for MLPs. While being very effective in evaluating most matches, these estimates usually overestimate the significance of matches in the presence of low complexity segments.

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Prognosis of different types of homeboundness among community-living older adults: two-year prospective study. The energy landscapes enable prediction of micromechanics of particle chains, which has implications in predicting the interfacial rheology of such particles at fluid interfaces. Scion-rootstock interaction affects the physiology and fruit quality of sweet cherry. The role of AT1 receptor in the changes in TH immunoreactivity of LC induced by brain cholinergic stimulation. The short-term outcome in 240 implants showed the ATS valve to be safe, to have a low incidence of complications, and to provide excellent hemodynamic performance. Process analysis was applied to examine the contribution of the individual processes to the species conservation equation. Theophylline prevented the decline of GFR, the increase of urinary beta 2-M and THP and the reduction of plasma EPO and PRA. Also, the scale and shape of distance dependence in contact probability was shown to differ depending on the production types of holdings.To demonstrate how the methodology may be used for risk assessment, disease transmissions via animal movements were simulated with the model cordarone tab 200mg used for analysis of contacts, and parameterized by the analyzed posterior distribution.

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