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Aldezole (Metronidazole)

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Aldezole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Amebidal, Anaerobex, Anaeromet, Anamet, Anazol, Camezol, Colpofilin, Dirozyl, Emedal, Etron, Flagemed, Geloderm, Lindoplus, Menizol, Metrobac, Metroderme, Metrolotion, Metronidazolum, Metrosil, Metrovax, Missilor, Molazol, Nidagel, Nidazol, Nidazole, Rosalox, Rozagel, Rozex, Trichex, Trichomonacid, Trichozole, Tricodazol

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Also known as: Metronidazole


Metronidazole injection is used to treat serious bacterial infections in different areas of the body. It is also used to prevent infections in the bowels before and after surgery for some patients.

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of your doctor.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Aldezole ER. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.


Single oral doses of Aldezole, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Aldezole has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Aldezole overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aldezole dosage information

Side effects

The most common side effects associated with Aldezole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Metronidazole should be used with caution in patients with active disease of the Central Nervous System. The treatment should be withdrawn in case of ataxia, dizziness, or confusion. The risk of aggravation of the neurological state should be considered in patients suffering from severe central and peripheral neurological diseases, fixed or progressive paraesthesia and epilepsy. Caution is required in patients with active disease of the central nervous system except for brain abscess.

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Although conventional medical treatment was not effective, drainage of chylothoracic pleural fluid significantly decreased after administration of octreotide acetate. Drug-eluting stents compared with bilateral internal thoracic artery grafts for diabetic patients. Involvement of nurses in the dying process of patients--nursing of a distressed patient with lung cancer who was aware of the nature of his illness. The origin of the N3 potential was also discussed, especially with respect to vestibular evoked potentials. Both producers use water with maximum 1 ppm free chlorine for vegetables rinsing, while the two processes differ by the number of washing cycles.

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As a result, 12 genes (fibronectin, VEGFR-1/Flt-1, VEGFR-2/Flk-1, alpha 5 integrin, Tek/Tie2, VE-cadherin, VEGFA, connexin 45, ShcA, cytochrome P450 reductase, CD148/DEP-1, and EphrinB2) were determined to play critical roles in vasculogenesis. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. We conclude that the addition of the cholesterol moiety limits the range of the protein and is required for maximal activity, while addition of palmitate is required for all activity. Cryptic diversity in a widespread North American songbird: phylogeography of the Brown Creeper (Certhia americana). Factors affecting accuracy included the co-purification of PCR inhibitors and/or fluorescence quenchers and the yield of target DNA in the extract. Evolutionary traces of thermophilic adaptation are manifest, on the whole-genome level, in compositional biases toward certain types of amino acids. At the same time, a variety of properties and features of DNA-hydrolyzing autoantibodies have been studied.

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Bacteria isolated from blood, stool and urine of typhoid patients in a developing country. Consistent with studies using elliptical-shaped polymers, the initial point of contact between the phagocyte and filamentous uropathogenic E. This case illustrates the use of repeated SRS, specifically Gamma Knife radiosurgery (GKRS) for management of a unique brainstem metastasis. The L1-encoded proteins (ORF1p and ORF2p) preferentially associate with their encoding transcript to form a ribonucleoprotein particle (RNP), which is a proposed retrotransposition intermediate. Various methods enable the preparation of platelet components and of highly concentrated components for local use according to standard blood banking criteria.

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The signaling mechanism involved in 16-kDa PRL action in endothelial cells remains unclear. Further research is needed on the diagnosis, neurobiology, and treatment of borderline personality disorder. Treatment of diabetic retinopathy with nandrolone-decanoate (Decadurabolin). Participants performed the handball 50 times (5 blocks x 10 repetitions) using either a massed (1 sec. Although the right ventricular pressure was 80 mmHg and the pressure gradient through the conduit was 38 mmHg, her general clinical condition was fairly good. However, an immediate reduction in the fluorescence signal is observed after addition of HDL to DHR, due to fluorescence quenching from lipid-probe interactions.

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Epidemiology of vestibular vertigo: a neurotologic survey of the general population. Through the detection on seed purity, 1 000-grain weight, water content, germination rate of D. Three hundred fifty-five abstracts were reviewed and 52 selected for full-text review that described information concerning pertinent aspects of labral formation, development, degeneration, biomechanics, and clinical results of labral repair or resection. The established renal epithelial cell line LLC-PK1 (proximal tubule) started to form multicellular spheroids within 24 h when grown in agar overlay culture. The BaP-DNA adducts were separated by Sephadex LH-20 column or high-performance liquid chromatography. Local delivery of paclitaxel with the double-balloon perfusion catheter to prevent restenosis in coronary stents is safe and efficient. A site-specific technique for cross-section transmission electron microscopy specimen preparation of difficult materials is presented. Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report.

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Animal experiments with signaling selective APC-variants show promise in improving the therapeutic efficacy and safety of APC in sepsis. Development of fibrous, cartilaginous and synovial joints, bone maturation and remodeling, and mechanisms leading to skeleton dysmorphogenesis are also discussed. 18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions. A new method of surgical treatment for retroperitoneal fibrosis is demonstrated on 3 patients. In contrast, a swollen duodenal papilla and the presence of extrapancreatic lesions are risk factors for relapse, and those AIP patients are candidates for maintenance corticosteroid therapy to reduce relapse. Although de novo structure determination still requires considerable effort, information on interaction surfaces from chemical shift perturbations is much easier to obtain. Biomagnetic and bioelectric detection of gastric slow wave activity in normal human subjects--a correlation study.

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Respiratory issues related to moderate prematurity include delayed neonatal transition to air breathing, respiratory distress resulting from delayed fluid clearance (transient tachypnea of the newborn), surfactant deficiency (respiratory distress syndrome), and pulmonary hypertension. Correlation between quantitative CT perfusion and tumor location is statistically significant only in subjects with localized high-volume, poorly differentiated prostate cancer. Raman spectroscopy has been applied to series of BEA- and BEC-type samples differing from each other in size, Si/Al ratio and polymorph percentage in order to analyse the effect of interlayer stacking arrangements on the vibrational modes of zeolite beta. Experiments were carried out with fully expanded leaves from three-week-old seedlings of wheat (Triticum aestivum L.) raised without NO 3 (sup-) . It also contains nutritional properties that can be used to treat metabolic problems. Compliance with good practice is less than ideal and education in impression disinfection for both dentists and dental technicians is required to address this. 1) Glucagon latently inhibits cholinergic motor activities in the antrum and intestine not directly, by binding to either receptor on the smooth muscle cells, but through postganglionic cholinergic neurons and possibly through 5-hydroxytryptamine neurons. In the biosynthesis of this antibiotic, a fatty acid-AMP ligase (FAAL) activates the starter unit hexanoic acid as acyl-adenylate and forwards it to an iteratively acting polyketide synthase.

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We retrospectively reviewed our first 96 consecutive cases (17 radical prostatectomies, 2 sacrocolpopexies, 6 adrenalectomies, and 71 renal procedures), performed between October 2001 and April 2003, of optical-access laparoscopic trocar placement as initial entry into the desufflated abdomen. Effect sizes indicated that the main effects of genetic and experiential risk were much better predictors of child internalizing problems than was their interaction. It is concluded that IL-1ra has certain regulatory effect on the immunologic function of lupus-like NZB/W F1 mice. Our understanding of the pathogenesis, prevention, and management of these lesions is constantly developing. However, the main problem concerns prophylaxis for persons exposed to an index case, because nonspecific immunoglobulins are recommended but unavailable in France for this indication. Vaginal flora were examined by Gram stain, and sociodemographic data were extracted from medical records. The film-coupled nanocube is of particular interest due to the formation of waveguide cavity-like modes between the nanocube and film.

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Life history collages: effects on nursing home staff caring for residents with dementia. Erythromycin estolate (EME), a potent macrolide antibiotic, generates free radicals, but their role in the development of liver toxicity is not yet well understood. Severe transient left ventricular pseudohypertrophy during treatment of hemophagocytic lymphohistiocytosis: a case report. Tissue transglutaminase contributes to the pathogenesis of preeclampsia and stabilizes placental angiotensin receptor type 1 by ubiquitination-preventing isopeptide modification. We also demonstrate that wild type IFI 16 can repress transcription of a reporter gene containing the minimal promoter region of the human cytomegalovirus UL54 gene. Bone scintigraphy in the diagnosis of chronic osteomyelitis in the maxilla. Influence of pulmonary bacteriology and histology on the yield of diagnostic procedures in ventilator-acquired pneumonia. Although the molecular characteristics of these unconventional ERs are still largely unknown, the generally held view maintains that plasma membrane ER (mER) originates from, or is related to, classical nuclear ERs.

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DNA fingerprinting in rice using oligonucleotide probes specific for simple repetitive DNA sequences. The screening of other malignancies associated with Lynch syndrome is more complex. To clarify the characteristics, survival and predictors of mortality in Japanese patients with pulmonary arterial hypertension (PAH) associated with CTD. Studies of gnotobiotic knockout mice that lack fasting-induced adipose factor (Fiaf), a fibrinogen/angiopoietin-like protein normally secreted from the small intestinal villus epithelium and suppressed by the microbiota, showed that Fiaf deficiency results in loss of resistance of villus endothelial and lymphocyte xenical pill populations to radiation-induced apoptosis. The Kolmogorov-Smirnov Two-Sample Test was utilized to determine whether two distributions are the same. brevidens (Sb4AX) repeat however, the molecular organization of this element in these two species evolved in a basically different manner. The endpoints of the study were the efficacy, survival and tolerance of patients. The Igakkan was an institute for medical education in Tokugawa Japan, which was founded by Taki Motoaka (1693-1766) in 1765 and became a bakufu institution in 1791. Quantitative studies on the behavior of the alveolo-capillary membrane in experimental oxygen deficiency.

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Drainage occurred through both the external and internal jugular venous systems. Two methodologies have been proposed for a simple statistical estimation of the detection limits in microbore-HPLC and CE techniques. Five years later another metastasis was resected from his left upper lamisil 1 cream generic lobe. By comparing release of DEHP from PVC medical devices and TI, safety of DEHP in PVC medical device can be evaluated. cinerea sclerotia by the mycoparasite, it extensively colonised the cortical and medulla areas by intercellular growth. Taste reception is fundamental to diet selection in many animals.

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Recurrent fever is a relatively common problem during childhood. Studies on infection, epidemiology, influence of bovine tuberculosis, disease forms and prevention in 3 districts of the Rhineland-Palatinate. A methodological study on subject-specific regression analysis (SSRA) exploring the correlation between the neural response and the subjective evaluation of emotional experience in eleven healthy females is presented. Performing the barium enema: equipment, preparation, and contrast medium. Microscopy showed that the targeted bubbles bound to blood clot whereas control, nontargeted bubbles did not bind to blood clot. Transforming growth factor-beta produces a biphasic effect on osteoclast generation induced by 1 alpha,25-(OH)2D3. In this study, we used feticide as a novel model of fetal brain damage. The ptsH1 mutation (Ser-46 of HPr replaced with an alanine) prevented the inhibitory effect of the hprKV267F mutation. The aim of this study was to investigate the predictors of amenorrhoea self-reported by patients who are suffering or recovering from eating or exercise disorders. Nine eyes received three monthly injections and 17 eyes received two bimonthly injections.

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The correlation observed between renal function and CK activity underscores that measurement of cystatin C is more accurate than creatinine alone in the evaluation of renal function and that it is unaffected by response to physical stress-induced muscular damage. Two-visit protocols for IUD insertion may represent a barrier to IUD uptake. Eye care professionals can play an important role in the early detection of multiple sclerosis (MS) since the disease often has ocular manifestations such as optic neuritis. This was however not the case with the other mollusk Crepidula fornicata, which seems to have undergone a reduction in intron number or intron size. A multicenter evaluation of how many infants with permanent hearing loss pass a two-stage otoacoustic emissions/automated auditory brainstem response newborn hearing screening protocol. This method is applied to the estimation of polyphenol recovery after ingestion of six different polyphenol-rich beverages. Systematic preventive rodents control: correlation between mode of finance and level of coverage. We analyzed the repeats and found that they contained two other genes, one encoding tryparedoxin peroxidase and the other encoding a 0.6 kb mRNA (named associated gene or AG) with sequences showing no significant similarity to those in the GenBank database. BAL IGRA performed poorly for the diagnosis of smear-negative TB in a high HIV/TB burden setting. Lubrication of the endoscope prior to nasendoscopy does not reduce levels of discomfort or pain for the patient, but increases ease in insertion for the operator.

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We reviewed data reported by the FBI Bomb Data Center for the years 1988-1997 and analyzed the number of bomb-related deaths and injuries and incidence of bombings. A receptor mutant of the tyrosine kinase (TK) domain only partially inhibited antiapoptotic signaling, whereas a mutant displaying constitutive autophosphorylation of the receptor did not show enhanced survival activity. The MIR Ab assay may be useful for predicting MG symptom severity, especially for discriminating between ocular and generalised types of MG. Uncommon examples of schwannomas are seen in which a coexisting glandular component is present. The adiponutrin risk variant is a common genetic determinant of progressive liver fibrosis. During the 8 hours of the night from 2200-0600 hours the membranes ruptured more frequently than during the 16 hours of the day. The result was compared feldene gel generic name with those for 6 patients with renal damage due to other diseases (mean creatinine: 6.2 mg/dl, blood urea nitrogen: 51.7 mg/dl) and for 8 healthy subjects. Recent collections in KwaZulu-Natal and Swaziland have led to the discovery of two new species of the flightless and highly threatened Scarabaeinae genus Gyronotus van Lansberge, 1874. With snoStrip we present an automatic annotation pipeline developed specifically for comparative genomics of small nucleolar RNAs.

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Preoperative c-m-DCs levels in the PBMC of patients with pancreatic cancer and DCs counts in the cancer tissue can be a prognostic factor after surgical resection. Specifications for toxicological assessment of new preparations have been prepared in the GDR and Poland and are described. Furthermore, medium supplemented with autologous human serum was more effective in promoting motility than medium with fetal bovine serum in all cases. To quantify traction forces at focal adhesions in an adherent cell, compliant substrates are used in conjunction with high-resolution imaging and computational techniques in a method termed traction force microscopy (TFM). lactiflora of the roots as asexual reproduction materials for cultivation experiment, morphological index, photosynthetic parameters and photosynthetic pigment content were measured. Vesicle lipids were fractionated into different classes and analyzed by either electrospray ionization- or gas chromatography-mass spectrometry. Moreover, we show that metazoan ALDH1s and ALDH2s are members of a single ALDH1/2 clade and that during evolution, eukaryote ALDH1/2s often switched between large and small SECs after gene duplication, transforming constricted channels into wide opened ones and vice versa. We also found that non-volant species are better indicators of endemism than volant ones at regional scales, but volant species are better indicators than was previously thought. A randomized trial of planned vaginal versus planned cesarean delivery is highly albendazole brand name desired. The treatment environment for retarded persons in nursing homes.

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In the present work we investigated the effects of 25 months of ethanol consumption on the antioxidant defense system in different organs of rats, in comparison with normal and aged animals. A young woman without remarkable medical history, experienced a life threatening anaphylactoid reaction after induction of general anaesthesia for an emergency curettage. Modified palate mouth gag tongue blade to prevent endotracheal tube compression. The aim of this study was to compare the metabolic effects of metformin and insulin on hyperglycaemia in ICU patients. We recently reported PRL receptor (PRLR) expression in mouse adipocytes and increased levels of PRLR expression in the adipose tissue of lactating and PRL-transgenic mice compared with controls. Trauma is known to be one of the strongest risk factors for pulmonary embolism (PE). Studies of the telomere protein inter-complex interactions and the switching of components between complexes provide insight into their fundamental roles of programming telomere length and configuration, and thus cell proliferative potential. Surprisingly, survival signaling was dependent upon tyrosine 950, the binding site for IRS-1, IRS-2, and Shc proteins.

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There were 225 clandestine laboratories seized in the United States of America in 1982, an increase of 23 per cent over 1981. The lymphocytes of line P chickens showed a higher phytohaemagglutinin (PHA) response than those of line V chickens and (P X V)F1 hybrids. Chiropractic lyceums: the colorful origins of chiropractic continuing education. Measurements of direct IAP obtained from the RFl, LFl, and V locations via abdominal cannulation and direct arterial blood pressures obtained via catheterization of the transverse facial artery were obtained in fasted, standing, unsedated horses. Subsequently, they were assigned a final clinical stage after radioisotopic bone scanning, lymphangiography and staging pelvic lymph node dissection. A study of radiation-induced aging: response of irradiated and nonirradiated mice to cold stress. The plant surface, which is representative of the phylloplane and rhizoplane, is a characteristic habitat for microorganisms. Two patients underwent surgical biopsies for diagnosis, one patient was unresectable and one patient underwent RFA of a dominant lesion.

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Interaction of TGF-beta(1) and iNOS plays a role in the pathogenesis of HPH in rats. The venous sacs exhibited severe phlebosclerosis of rapid progression and gross loss of muscle, and elastica was most prominent at the fundus. Laboratory-analogue Kinneyia were formed via the sedimentation of glass beads, which preferentially deposit in the troughs of the ripples. The aim of this study was to report this situation after CCRS plus HIPEC, which has not been described yet and for which the treatment is not yet well defined. However, another trap line adjacent to a nearby residential area yielded four Norway rats in 510 trap-nights. Results also highlighted that traditional pain indicators, such as fluctuations in haemodynamic parameters, are not always an accurate measure for the assessment of pain in unconscious patients and as such more objective pain assessment measures are essential. Human fibrosarcoma cells (HT1080) were incubated with doxorubicin, mafosfamide and trabectedin both alone and in combination with taurolidine and TRAIL. The thrust towards patient-centred medicine, the promotion of open and negotiative consultation skills and the development of a biopsychosocial model of primary care medicine all rely on the patient providing a history composed of more than a list of facts. This paper concerns one of the main problems facing continuing nurse education, that of matching the learning needs of the individual nurse with the needs of the care setting.

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