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Alendronate

Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Alendronate is for use when you have a high risk of bone fracture due to osteoporosis. Alendronate is also used to treat Paget's disease of bone.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

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Albenza, Daklinza, Robaxin, Nuvigil, Aldactone, Nolvadex, Lipitor, Craveril, Betam, Ativan, Norgest, Lizocas, Vermiz, Zalvon, Budesonide, Calday,

Description

Alendronate (alendronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Alendronate is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids.

Alendronate is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.

Dosage

Take Alendronate exactly as prescribed by your doctor. Alendronate is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Alendronate first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Alendronate tablet. Swallow the tablet whole.

For at least 30 minutes after taking Alendronate:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Alendronate. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Alendronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Alendronate is often given for only 3 to 5 years.

Detailed Alendronate dosage information

Overdose

Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendronate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Alendronate if you are allergic to Generic Alendronate components. Be very careful with Generic Alendronate if you are pregnant or planning to have a baby, or you are nursing mother. Generic Alendronate can harm a baby. Be careful with Generic Alendronate if you suffer from or have a history of low blood calcium (hypocalcemia), a vitamin D deficiency, kidney disease, an ulcer in your stomach or esophagus. Be careful with Generic Alendronate if you are taking aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve); cancer chemotherapy; or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Do not stop take it suddenly.

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The purpose of this study was to undertake a computational modeling analysis of the deposition kinetics of a magnetite nanoparticle agglomerate in cell culture medium. In the present article, we report 14 cases of patients with different tumors, injured or died after a traumatic episode. Effect of chelating agents and phosphoramidon on the L-leucine transport system in microvillar vesicles from pig kidney. Shortsighted dislocations and political interference have deprofessionalized and decimated our ability to control, rather than to destroy, the governance of bureaucracy. To establish reference intervals for major haematological and biochemical parameters in Gabonese infants and children. Two cases of lactobezoar formation were seen in premature low-birth-weight infants in a 24 cal/oz formula fortified with medium-chain triglycerides and glucose polymers given by continuous nasogastric infusion.

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Effective primary prevention programs in public health and their applicability to the prevention of child maltreatment. Depending on the prevailing conditions, acetate can be used byR. The XLMR group is currently comprised of 105 highly varied types of retardation that can be associated with a fragile X chromosome, biochemical defect, neurologic alterations, bony dysplasia and a range of malformations. Mechanical thrombectomy is an alternative way to go: the European experience commentary on: quality improvement guidelines for percutaneous management of acute limb ischemia. Abnormal duodenal loop: influence on basal and food-stimulated motility pattern. In spite of the comprehensive multidisciplinary approach to the management of this disease, the prognosis remains dismal. The Dutch Lower Extremity Functional Scale was highly reliable, valid and responsive in individuals with hip/knee osteoarthritis: a validation study. Recently published outcomes data demonstrate feasibility, safety and reproducibility for LESS in gynaecology. The maturity of the auditory system influences ABR responses in infants. Upon designing and implementing a literature course on family values for Year 4 medical students, we found that while the supposed benefits of literary inquiry were to lead students to a deeper understanding of difficult issues such as illness and violence in the family, many of our students were unable to engage critically with the course material.

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Evidence of immune system abnormalities in adult schizophrenia has prompted examination of the human leukocyte antigen (HLA) system. Click aspartic acid as H ILIC SPE material for selective enrichment of N-linked glycopeptides. Totally thoracoscopic repair of atrial septal defect without robotic assistance: a single-center experience. If CSD propagation is confirmed to be more effective from posterior to anterior regions in other species, this may be relevant to the pathophysiology of classical migraine because the most frequent aura symptoms (i.e., visual disturbances) originate in the occipital cortex. Membrane interaction of segment H1 (NS4B(H1)) from hepatitis C virus non-structural protein 4B. The critical D and iD units are GlcUA(2-O-sulfate)beta1-3GalNAc(6-O-sulfate) and IdoUA(2-O-sulfate)alpha1-3GalNAc(6-O-sulfate), respectively, where IdoUA represents L-iduronic acid.

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Four patients showed rises of antibody titres to Candida and two to Aspergillus fumigatus. Repression of delayed hypersensitivity to conjugated serum albumin during immune paralysis induced in guinea pig by heterologous proteins. The demographic projections estimated for Morocco indicate that between 2010 and 2030, the expected annual number of hip fractures would increase about twofold. Acinar cell basal-lateral membrane-endomembrane traffic may mediate interactions with both T cells and B cells. The extreme thermal stability of proteins from hyperthermophilic organisms is widely believed to arise from an increased conformational rigidity in the native state. We myambutol set out to see whether the surface of new ruffles arises from neighbouring membrane, or whether it comes from an intracellular pool of endocytosed membrane.

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In-process measuring of the electrical shunt resistance of laser-scribed thin-film stacks by nested circular scribes. Synthetic leonourine showed uterotonic activity in vitro and in vivo, just like its naturally occurring counterpart. Environments are patchy in not only abiotic factors but also biotic ones. Two experiments, each consisting of 21 maize populations of known pedigree, were grown at three and four environments in Minnesota in 1991. Other microfilament- and microtubule-dependent processes appear normal in cyk-1 mutant embryos, indicating that cyk-1 regulates a specific subset of cytoskeletal functions. Idiopathic cranial pachymeningitis - diabetes was not the brains. Reconstructive lower urinary tract surgery in incontinent adolescents with exstrophy/epispadias complex.

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From March 1995 to June 2002, tendons rupture and tendons defect were repaired by ultra-deep-low-temperature allogeneic tendon grafts in 96 cases, including 51 cases of flexor or extensor tendon defect of hand, 36 cases of coracoclavicular ligament rupture, 4 cases of cruciate ligament rupture, 2 cases of calcaneus tendon rupture and 3 cases of extensor tendon defect of foot. Herein, we evaluated postoperative lung cancer recurrence and the personalized postoperative surveillance periods and methods used. Therefore, a better understanding of factors that control MCT1 function may be the key to better understanding the origins and treatment of pathological lactic acidosis. Management of exstrophy of the urinary bladder by primary closure. The tissue slurry was mechanically disaggregated and separated by hytrin brand centrifugation on a Percoll density gradient. This points to a role of copper in CO binding by terminal oxidases. Dose levels of the occupational radiation exposures in Poland based on results from the accredited dosimetry service at the IFJ PAN, Krakow. Dangerous situations are created by heavy workloads, and are aggravated by sub-optimal skill-mix, poor communication and individuals making mistakes or not following accepted procedures. Employing highly purified human monocytes as a starter population, low concentrations of Il-4 (25 U/ml) and GM-CSF (3 U/ml) in combination with Dexamethasone (Dex) (0.5 microM) in serum-free medium trigger the differentiation into FDC-like cells.

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Due to advances in medical research, more and more diseases can be cured nowadays, which largely increases the need for an easy-to-use software in calculating sample size of clinical trials with cure fractions. The development and efficacy tests for the autoclave indicator tape. Glucagon-like peptide-1 reduces the pulsatile component of testosterone secretion in healthy males. Omega 3 fatty acid status in patients with retinitis pigmentosa. We have evaluated the effects of the volume and speed of administration of local anaesthetic during peribulbar anaesthesia. She is free of disease 36 months postoperatively and is now considering in vitro fertilization using a surrogate. Muscle tension receptors in animals monitor the tension generated by muscles. Can one establish a relationship between birth rate and community development?. A case of 50 years old man with tuberculosis of scrotum is reported here that presented with non-healing ulcer on ventral surface of left hemiscrotum for the last one year.

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