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Alfacip (Calcitriol)

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Alfacip is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Alfacip is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Admax, Alfabond, Alfacal, Alfacalcirol, Alfarich, Alphadol, Apcical, Arachitol, Aristrol, Biocitral, Bonestat, Calasto, Calcibest, Calcikind, Calcit, Calcitriol, Calcor, Calday, Caldikind, Caldix, Calfa, Caltop, Calzem, Carcal, Cholical, Citroj, Coecoral, Devita, Estovon, Minroset, Nutribone, Osteobel, Ostriol, Politrol, Rockbon, Septriol, Solbiocal, Statbone, Trolec

Similar Products:
Famvir, Myambutol, Valium, Effexor, Silagra, Bumeftyl, Navalin, Loratia, Onzil, Tevafos, Citola, Zitromax, Nilacid, Cetrich, Perindo,

Also known as: Calcitriol


Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D is necessary for strong bones and teeth.

Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. Your doctor may treat these problems by prescribing vitamin D for you. Vitamin D is also sometimes used to treat other diseases in which calcium is not used properly by the body.

Ergocalciferol is the form of vitamin D used in vitamin supplements.

Some conditions may increase your need for vitamin D. These include:

Alcoholism Intestine diseases Kidney disease Liver disease Overactivity of the parathyroid glands with kidney failure Pancreas disease Surgical removal of stomach

In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a vitamin D deficiency. Increased need for vitamin D should be determined by your health care professional.

Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of vitamin D used to treat hypocalcemia (not enough calcium in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.

Claims that vitamin D is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from vitamin D supplements; however, controlled studies have not been performed.

Injectable vitamin D is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking vitamin D on your own. Taking large amounts over long periods may cause serious unwanted effects.


This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Alfacip. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.


If you overdose Generic Alfacip and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alfacip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Antigenic cross-reactivity between 7 S and 19 S ra bit gamma-globulin. These results indicate that chronic morphine exposure does not result in tolerance of the SO to the spasmogenic effects of morphine. Possible association between tardive dyskinesia and altered carbohydrate metabolism. Flaviogeranin, a new neuroprotective compound from Streptomyces sp. Modern laboratory technic--beginning of automated laboratory diagnosis. To better understand the potential of natural herbs in treating chronic inflammation and to identify their mechanism of action, we have evaluated the anti-inflammatory activities of 20 medicinal herbs commonly used in the Hispanic culture. Voltage clamping the preparation at the MDP during superfusion of 0.2 mM Ba revealed a time-dependent, inwardly directed current.

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Both Ca125 and Ca250 could decrease the ratio of 24-hour urinary Hop/Cr. The mechanism of melanoma-associated thrombin activity and von Willebrand factor release from endothelial cells. Success in preventing recurrence of fluid at one month, using up to 2 doses of each drug, was 14 of 16 cases for Corynebacterium parvum, 5 of 9 for tetracycline given via an intercostal needle, and 6 of 7 for tetracycline given through an intercostal tube. In this manner, the mutation was mapped within a 485-bp DNA segment in the central region of the genome at the extreme right end of the HindIII D fragment. Isolated rat hearts were perfused initially by the Langendorff mode with Krebs-Henseleit buffer (KHB) for 15 minutes in the absence (control) or presence of losartan (4.5 micromol/L) and/or HOE 140 (10 micromol/L). After a recovery period, we analyzed global DNA methylation patterns in the irradiated and control cells using the methylated-CpG island recovery assay (MIRA) method in combination with high-resolution microarrays. They will probably have a modest impact on drug-resistant epilepsy. Pigmented Villonodular Synovitis of the Hand in the Asian Population.

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Functional interactions of the domains of the adenovirus DNA binding protein. All our findings suggest that the mechanism underlying the anorexigenic action of OXM is similar to that of glucagon in chicks. Human interaction as environmental enrichment for chimpanzees (Pan troglodytes) and other primates is widely promoted and believed to be of value, but has been subject to little objective evaluation. Tissue-engineered heart valve scaffolds fabricated from polyhydroxyalkanoates can be used for implantation in the pulmonary position with an appropriate function for 120 days in lambs. Here we report that selection for behavior and maternal methyl-supplemented diet alters rat hippocampus glucocorticoid receptor (GR) mRNA expression. The results of treatment with amphotericin B, itraconazole, or both were variable.

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Prospects and possibilities in the development of behaviour therapy. Contributory reasons are explored, along with suggestions on how to ensure that NICE can help ensure effective and equitable services. Effects of X-radiation on the development of the cholinergic system of the rat brain. Esophageal function following sclerotherapy of esophageal varices. Adrenergic and serotonergic receptor responsiveness in depression. Previous attempts to model collective motion have primarily focused on group behaviours of identical individuals.

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The paper argues that their main contribution is in the modelling of how individual reacts to incentives (including those provided by public policies). Several aspects of the chemiluminescence method for determining enzymatic activity in crude tissue extracts are discussed. An infant born after a short period of intrauterine growth retardation may not necessarily be small for gestation at birth. Inhibition of early steps in the coagulation cascade with the inhibitor of tissue factor-factor reviews on norethindrone birth control VIIa complex, or with activated protein C, also appears to be an effective anticoagulant strategy. In this study, we examined the impact of either wild type or a bromo-deficient p300 on the expression of several p300-dependant genes. elegans sex determination protein MOG-3 functions in meiosis and binds to the CSL co-repressor CIR-1. Both neutral and acidic extracts of the tumor contain an immunoreactive FGF (ir-FGF) that cross-reacts in a parallel and dose-dependent fashion in the radioimmunoassay. A second group was trained to discriminate between 56 mg/kg theophylline and saline. In contrast, those patients who were PCR negative either had inactive disease or had been appropriately treated and did not respond to additional antibiotics, and all four control urine specimens were PCR negative. Expression of TNF-alpha messenger RNA in the lung after LPS administration was significantly reduced by rTFPI administration.

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A method to accurately determine the extent of solid-phase reactions by monitoring an intermediate in a nondestructive manner. Complexed antigen, in fact, is taken up with high efficiency thanks to Fc receptors borne by APC. Collagens I, III, and V form heterogeneous fibers that account for the thickness of the lamina reticularis. The experimental curve for human eyes shows a slightly steeper descent toward the zovirax cream cost canada periphery than the theoretical curve. Nevertheless, inadequate transfection efficiency of target cells with current nonviral systems still limits the utility of this therapy.

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HIV-1 epidemic among female bar and hotel workers in northern Tanzania: risk factors and opportunities for prevention. They evaluated the reliability of this scale in 50 normal volunteers. Right ventricular overload in the light of vectorcardiographic interpretation. It is suggested that there is a need to establish an operational definition of negativity in carcinogenesis, with the realization that this definition may be revised in light of new information. This sequence is an Ik-1 respondive, functionally negative element as demonstrated in the context of both natural KOR and heterologous promoters. A fatal case of meningoencephalitis due to a leptomyxid ameba in a patient with the acquired immunodeficiency syndrome is presented.

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Oxidative damage by ruthenium complexes containing the dipyridophenazine ligand or its derivatives: a focus on intercalation. Sports and exercise cardiology in the United States: cardiovascular specialists as members of the athlete healthcare team. The increase in ribosomal protein synthesis was not accompanied by a corresponding decrease in non-ribosomal protein synthesis. We present a case where ultrasound demonstrated an inflamed appendix and a scrotal abscess, allowing the correct surgical management in a difficult clinical situation. A year of treatment with carbidopa and levodopa in Parkinsonian patients. Epidemiology of asthma in children, with particular reference to wind speed and wind direction. Influence of triiodothyronine albendazole 400 mg uses on the polypeptide composition of the intestinal brush border membrane during amphibian metamorphosis.

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A short-chain analog of lipid hydroperoxide, t-butyl hydroperoxide (t-BHP), can be metabolized to free radical intermediates by cytochrome P-450 in hepatocytes, which in turn can initiate lipid peroxidation, affect cell integrity and result in cell injury. The data obtained indicated that CS-A-3beta had a backbone consisting of alpha-D-1,4-linked GalpA residues and beta-L-1,2-linked Rhap residues with branches at C-4 of Rhap residues and C-3 of GalpA residues, composed of arabinogalactan and glucobiose. Fimbriae belong to a class of extracellular filamentous proteins which are involved in the attachment of bacteria to host tissues. Effects of x-irradiation upon spontaneous and evoked brain electrical activity in cats. ECV was calculated as GFR divided by GFR/ECV, both corrected for the one-compartment assumption. Clinical utility of erythrocyte sedimentation rate and plasma protein analysis in the elderly. After AMI, the degree of psychopathological symptomatology reduced during treatment more rapidly than that in patients with AH and in those with CHF. Dynamic MRI was performed in a patient with PVNS just before and 1 week and 3 years following synovectomy of the knee. Extraction and quantification of lignan phytoestrogens in food and human samples. Cardiovascular risk factors and diseases precede oral hypoglycaemic therapy in patients with type 2 diabetes mellitus.

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L-Cysteic acid and taurine were not suitable sulfur sources to support the growth of F. Antitrochanteric degeneration was detected in birds aged 20 weeks or older but histological examination identified lesions in others with grossly normal antitrochanters. The antitumor agent flavone-8-acetic acid (FAA) is remarkable because it induces hemorrhagic necrosis, altered tumor blood flow, and cytokine synthesis. Pediatric trauma patients: differences and implications for emergency nurses. For the reduction of N-hydroxylated derivatives of strongly basic functional groups, such as amidines, guanidines, and aminohydrazones, an oxygen-insensitive liver microsomal system, the benzamidoxime reductase, has been described. To analyze the epidemiological, clinical and neuropathological data of cases of cerebellopontine angle (CPA) tumors. Quinapril free base forms a stable salt with tris(hydroxymethyl)amino methane not reported earlier. The genotype of the principal Mycobacterium bovis in Argentina is also that of the British Isles: did bovine tuberculosis come from Great Britain?. Effect of flutoprazepam on skills essential for driving motor vehicles. Therefore, the cis-DDP adducts are only present on one strand of each of the two templates and are regularly spaced by 18 pyrimidine bases.

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