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Almac (Alprazolam)

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Almac is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Almac is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Almac may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Albiz, Aldep, Alpracon, Alpramax, Alpranex, Alpronit, Alproz, Alzopam, Anxyl, Aryalam, Azicalm, Balzam, Deproz, Dizeral, Emlol, Enxolam, Esteem, Faxtin, Indolam, Isorest, Normatine, Ozolam, Prozam, Rezolam, Richpram, Rivcam, Selamb, Silam, Suzilam, Tenzorid, Visram, Zocam, Zodia, Zoloid

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Also known as: Alprazolam


Almac is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Almac is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Almac if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Almac or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Almac. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take Almac XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Almac XR may be habit-forming and should be used only by the person it was prescribed for. Almac XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Almac extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Almac XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Almac XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Almac XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Almac XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Almac XR dosage information


If you have been prescribed Almac for medical reasons, the best way to avoid a Almac overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Almac consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Almac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Degree of obesity as measured by BMI Z score and tonsil size are significantly related to severity of OSA as reflected by the AHI, although the correlation is mild. alpha 2-C10 inhibits adenylyl cyclase more efficiently than alpha 2-C4. To assess the effects of dietary exclusions for the treatment of established atopic eczema. Hearing will be restored provided no irreversible changes of the VIIIth nerve and/or the inner ear have occurred. Electron spin resonance (ESR) experiments on LUVs with nitroxide spin probes positioned at the membrane/aqueous interface (5-doxyl stearate and CAT16) showed that LUVs in 2H2O have a broader splitting, Amax, at the membrane/aqueous interface than do LUVs in H2O.

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Immune complexes in serum of rats during infection with Plasmodium berghei. With respect to the cerebral edema that can be associated with the carmustine implants, there can appear images in follow-up that are suggestive of relapse. Patients had a tendency to endorse somatic symptoms indiscriminately. On the other day, an initial 50-min euglycemic period was followed by a 50-min hypoglycemic period. The retrospective assessment of surgical resection in the management of small cell carcinoma of the lung. Fast Fourier transform (FFT) and wavelet analyses are two methodologies that have proven to be useful in this context. Establishment of feather follicle stem cells as potential vehicles for delivering exogenous genes in birds. A lower-extremities kinematic comparison of deep-water running styles and treadmill running. Survival time within a disabled submarine (SUBSUNK) is dependant on atmospheric composition and proper design and use of emergency atmospheric control systems. Similarly, the pressor response elicited by the injection of nipecotic acid into the nucleus tractus solitarius was totally unaffected by the GABAA receptor blockade with bicuculline.

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Bone bruise in magnetic resonance imaging strongly correlates with the production of joint effusion and with knee osteoarthritis. To assess the impact of extremely preterm birth (24-26 weeks of gestation) on the mental health of parents two to six years after delivery, and to examine potential differences in post-traumatic growth between parents whose newborn infant died and those whose child survived. A four-quadrant subthreshold mode multiplier for analog neural-network applications. Sex differences in control of renal outer medullary circulation in rats: role of prostaglandins. The mobilities of lectins on the gel showed various degree of retardation with their affinity toward their macromolecular ligand-agarose. These findings indicate that epidemiologic studies designed to evaluate methyl mercury toxicity must take into account the multiple environmental burdens that can affect the population cumulatively and simultaneously. Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination. Inflammation and parietal cell atrophy was observed after 12 wk of H. In contrast, staurosporine reduced the invasiveness of only 1 of 4 ras-transformed cell lines. Pentoxifylline did not significantly influence TNF-induced RNI production.

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The studies were performed by electron diffraction and electron microscopy in high-resolution mode. Participation in the 1992 World Diabetes Day in the Ammerland district--a contribution to health promotion. A number of options currently exist for reconstructing such defects, including skin grafts, myocutaneous flaps, and free vascularized flaps. In a cholestatic infant showing hypoglycemia and cardiac failure, non-ketotic medium-chain dicarboxylic aciduria was disclosed by urinary organic acid analysis. In addition, disturbances of these neuropeptides could contribute to other symptoms such as increased physical activity, hypotension, reduced sexual interest, depression, and pathological feeding behavior.

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proteins which were able to bind noncovalently with mouse factor B were found in cells that are nonsecretors of factor B such as mouse-established monocytic cells and L cells but not in peritoneal resident macrophages. Alveolar macrophages from patients with inactive sarcoidosis compared with cells from healthy subjects showed increased spontaneous secretion of TNF-alpha and IL-6 only, whereas the constitutive release of IL-1-beta was similar as in healthy volunteers. Bacterial proteins and CpG-rich extrachromosomal DNA in potential cancer therapy. Alterations in perfused capillary morphometry in awake vs anesthetized brain. A mathematical model, quantified with respect to discrimination and calibration was then applied to the validation set of 36 patients. This model is used to estimate the size of the susceptible fraction and the correlation between the frailties of the twin partners. The use of both techniques lead to correlate relative and absolute elemental concentrations.

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That the CQI cycle resulted in improved performance suggests that an effective psychosocial training program for residents in ambulatory primary-care general internal medicine can be organized around CQI and a problem-oriented system of care. The new maximum-likelihood (ML) estimator was evaluated by Monte Carlo simulations. The results indicate plasticity in the expression of VIP- and PHI-IR in adult sympathetic neurons in vivo, and suggest that the changes previously seen in organ culture were primarily a response to axotomy. An O-conotoxin from the vermivorous Conus spurius active on mice and mollusks. These observations suggest the need for further studies on the role of Mycoplasma in the pathogenesis of advanced periodontal infections. During the initial hours of reaction, first order kinetics can be applied, where the short term first order rate constants for consumption of MnO(4)(-) and oxidation of PCE are 0.05-0.5 h(-1) and 0.5-4.5 h(-1), respectively. Serum and peritoneal fluid were collected from all patients undergoing laparoscopy. Neither room nor hearing-aid noise appeared to affect the results significantly.

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These studies are the first to show the time course of tolerance development and the magnitude of morphine tolerance in a non-mammalian vertebrate species. Obese subjects with insulin resistance and hypertension have abnormal aortic elastic function, which may predispose them to the development of left ventricular dysfunction. The psychosociological assessment of suicidal behavior among soldiers. The interaction with DNA was evaluated by circular dichroism (CD), electrophoresis and atomic force microscopy (AFM) techniques showing slight but significant structure-dependent differences among the evaluated complexes. We analyzed this and discussed its potential as a modality to complement SLNB. Cells respond on extremely low concentrations of autoinducer: only one or two molecules per cell are sufficient. The MAP, CCO, SV, and SW decreased significantly during hemorrhagic shock, and then gradually increased to baseline levels during and 1 hour after resuscitation. Endothelins release tissue plasminogen activator and prostanoids. NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet.

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Temperature-dependent expression of flagellar motility genes is mediated by the opposing activities of MogR, a DNA-binding transcriptional repressor, and DegU, a response regulator that functions as an indirect antagonist of MogR. dendrobatidis, but also provides information that increases the confidence of detection through histological surveys. First, it binds to the native enzyme in soluble extracts prepared from isolated chromosomes and effectively depletes such extracts of active enzyme. In conventional biochemical tests, 12 isolates were shown to belong to biovar EF-4a and 3 isolates to EF-4b. Abrogation of LAK activity was also observed when the effector cells were pre-exposed to plasma or when effector and target cells were simultaneously mixed with plasma and trapped in a fibrin clot. Specific attention is given to the familiar setting and to the motives which lead to the interruption of the nursing relationships. Many NT-ir cells were seen in the intermediate and ventral parts of the LS at the rostral and middle levels.

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Differential reelin-induced enhancement of NMDA and roxithromycin 300 mg AMPA receptor activity in the adult hippocampus. To describe the biomechanical and wound healing characteristics of corneas after excimer laser keratorefractive surgery. Spinocerebellar ataxia 14: novel mutation in exon 2 of PRKCG in a German family. NMR demonstrated a marked decrease in 2,3-DPG and an increase in inorganic phosphate after the first week of storage. West Nile virus (WNV) and hepatitis E virus (HEV) have emerged as members of transfusion transmitted infection.

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A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells. Basal RANTES promoter activity differs considerably among different species of monkeys: implications for HIV-1/AIDS progression. Their molecular weights were 59,000 for HAP1, 53,000 for HAP2, and 31,000 for HAP3. The formation of the additional binding sites was found to depend on the activity of the receptor preparations as well as on the mutual influence of the two main toxin-binding sites. Obesity is associated with a greater prevalence of asthma in children with no evidence of a significant modulation by either gender or age. The assessment included a structured neurological examination, psychometric tests using the WISC-R (in subjects born in 1981-82), a test of visuomotor integration (Beery), and a school questionnaire. Propranolol administration prevented the increase in conjugated diene level in the soleus muscles of hyperthyroid cat but not the malonaldehyde level.

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The possibilities for early diagnosis in primary open-angle glaucoma. Introduction of the deletion into wild-type virus resulted in recombinants which on intracranial inoculation of mice were avirulent. Inhibition of graft arteriosclerosis by modulation of the inflammatory response. Congenital malformations: a model predictive based on risk factors. Acquisition of the organisms is discussed, together with the different methods of infection (feeding on plants and through membranes or following injection) and the effect they have on the inoculum dose. Based on the available evidence, the recommendation for intrathecal infusion systems for cancer-related pain is moderate recommendation based on the high quality of evidence and the recommendation is limited to moderate based on the moderate quality of evidence from non-randomized studies for non-cancer related pain. 567 patients with asthma who were on regular maintenance therapy. The effect of irradiation on the duration of cell cycle phases was estimated by following the BrdU-labeled cells through the cell cycle.

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The results suggest that further dissection of T-cell subpopulations may clarify our understanding of this disease process. Selected images of the corneal layers were evaluated qualitatively for the shape and degree of light reflection of the microstructures. N4-acetylsulfatroxazole, taken as parent drug, is eliminated by renal excretion (92 per cent of the dose). Although the clinical efficacy of aminoglycosides is unsurpassed, these antibiotics nonetheless have an inherent tendency to produce undesirable side effects. Extinction was estimated by the expression of freezing behavior during repeated extinction trials (i.e., repeated exposure to contextual fear conditioning) on consecutive days.

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Antiaggregant drugs: their pharmacology, mechanism of action and the interpretation of large trials. The aim of current study was to investigate the expression levels of RFC2 and proliferating cell nuclear antigen (PCNA) in gestational trophoblastic diseases (GTD) and to explore the relationship of expressions of two proteins with GTD. Effects of riboflavin analogues and diuretics on the spontaneously hypertensive rat heart. Radiolabeled (18)F-F(2) was produced via the (20)Ne(d,alpha)(18)F reaction, and (18)F-acetyl hypofluorite ((18)F-AcOF) was generated by passing (18)F-F(2) through a column filled with tightly packed KOAc/HOAc powder. Interhemispheric communication is primarily mediated via the corpus callosum (CC), however with advancing age the anterior half of the can you take lamisil with antibiotics CC undergoes significant atrophy. Parameters can be estimated which separately characterize the agonist properties of the compound and its functional interactant effect. Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets. A reduction of collagen type III was reported in a single case, but no consistent biochemical or structural changes are detectable. Arthroscopic drilling with debridement of remaining cartilage for osteochondral lesions of the talar dome in unstable ankles. Deficiency of the cyclin kinase inhibitor p21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoimmunity.

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The resulting method corrects for product yield variations among replicate amplification reactions, permits resolution of homozygous and heterozygous genotypes based on endpoint fluorescence signal intensities, and readily identifies imbalanced allele ratios equivalent to those arising from gene/chromosomal duplications. The objective of this study was to assess the factors associated with the traffic mortality in the region of Central Macedonia in order to produce evidence in building up preventive policies. The harvested plasma was analysed for ciprofloxacin by high-performance liquid chromatography. Formerly a research tool, today, standardized DNA-ICM has become a useful and low-cost laboratory method to establish objectively and reproducibly an early diagnosis of prospectively progressive cervical intraepithelial lesions at a high-quality level. Activity was most stable between pH 6.5 and 9.0 for the trypsin-like protease and pH 8.0 for dipeptidase.

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The characterization of Ia expression during Sindbis virus encephalitis in normal and athymic nude mice. Competition between phase-matching and stationarity in Kerr-driven optical pulse filamentation. Do women and men consider abortion as an alternative to contraception in the United States?. To examine the association of echocardiographically determined left ventricular mass with incidence of coronary heart disease in an elderly cohort. We report what we believe to be the first case of a baby with an isolated Dandy-Walker malformation which was diagnosed prenatally and was subsequently found to have a trisomy 9 mosaic syndrome. Sensory afferent projection patterns within organotypic explants of fetal mouse spinal cord-dorsal root ganglia (SC-DRG) were mapped out histologically using an HRP-staining method. Pathologic fractures are not commonly described in primary hyperparathyroidism. An endogenous inhibitor of the protein tyrosine kinase activity of normal and malignant human lymphoid cells.

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A method for the diagnosis of disc herniation and nerve root compression in the lower lumbar and upper sacral spine is presented. A review of the literature shows that it is recommended to wait 4 to 8 weeks before changing treatment if the response is insufficient. fastidiosa rpfC mutants hyperexpress rpfF and overproduce DSF and are deficient in virulence and movement in the xylem vessels of grape. Changes in vision efficiency determined by a black and white chess board were monitored during and after 1 h exposure to 4 levels of noise: 90 dB-A, 93 dB-A, 96 dB-A or 99 dB-A and 2 h exposure to 96 dB-A. High-throughput DNA sensors capable of detecting single-base mismatches are required for the routine screening of genetic mutations and disease.

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No author has a financial or proprietary interest in any material or method mentioned. Genome-wide evidence for local DNA methylation spreading from small RNA-targeted sequences in Arabidopsis. Our results suggest that in MS patients abnormal kappa/lambda ratios are also restricted to IgG components in CSF, as oligoclonal IgG bands are. Determination of protonix dosing pediatrics nitrate concentration in soil via photoacoustic spectroscopy analysis of ion exchange membranes. Pathomorphological changes in ovaries were more evident and complex, concerning all structures of the gland. Studies on equilibrium binding of riboflavin to dopa-melanin and some spectroscopic characteristics of flavin-melanin complex.

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Multidrug-resistant Escherichia fergusonii: a case of acute cystitis. Human lung is a major target organ for all inhaled drugs, environmental toxicants and carcinogens. The causal trauma was penetrating in 11 cases and blunt in five. Described is the ultrastructure of the subepithelial capillaries and venules in the forestomach, of sheep. The changes are most probably due to changes also found in the organ functions. Basic fibroblast growth factor (bFGF), epidermal growth factor (EGF) but not platelet-derived growth factor (PDGF) induced an increase in the number of cells positive for the ganglioside-recognizing monoclonal antibody, A2B5.

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Kinesiographic records were acquired using K7I and positioning a magnetic sensor frame integral with the head and with the sensory field balanced on an artificial magnet adhering to the mucosa covering the roots of the lower mandibular incisors. Otoneurologic evaluation in children with school difficulties: vestibular function investigation. The discussion outlines the evolutionary importance of considering variation in the reproductive success of different individuals. GERD is a clinical syndrome involving the reflux of gastric contents into the esophagus. The BMI proposed at this study configure with as the more adequate alternative to the screening for the scholars with increased chances to carry DCV risk factors. Two hundred and twelve non-diabetic subjects (158 with normal glucose tolerance and 54 with impaired glucose tolerance) were enrolled in this study.

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