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Almazine (Lorazepam)
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Almazine

Almazine is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal. It is used to treat chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It can be given by mouth or as an injection into a muscle or vein. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Lorpam, Lorvin, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Elavil, Rhinocort, Diovan, Furadantin, Avodart, Ciprofloxacinum, Dezrolala, Coxet, Ecmin, Losalet,

Also known as: Lorazepam

Description

Almazine, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or intravenous routes of administration.

Almazine is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Almazine affects chemicals in the brain that may become unbalanced and cause anxiety. Almazine is used to treat anxiety disorders.

Almazine may be habit-forming and should be used only by the person it was prescribed for. Almazine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Dosage

Usual Adult Dose for Anxiety:

Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day Maintenance dose: 1 to 2 mg orally 2 to 3 times a day Comments: -The daily dosage may vary from 1 to 10 mg/day. -The dosage should be increased gradually when needed to help avoid adverse effects. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Usual Adult Dose for Insomnia:

2 to 4 mg orally once a day at bedtime Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Use: Management of insomnia due to anxiety of transient situational stress

Usual Geriatric Dose for Anxiety:

Older or debilitated patients: -Initial dose: 1 to 2 mg orally per day, given in divided doses Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -The daily dosage may vary from 1 to 10 mg/day. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Detailed Almazine dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Almazine can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Almazine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Almazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Almazine Injection.

Extreme caution must be used when administering Almazine Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Almazine injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Almazine Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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It is widely agreed that complex diseases are typically caused by the joint effects of multiple instead of a single genetic variation. We are reporting this case because of its rare and unusual site of occurrence and so far, in the available literature, no such case has been reported on tumours of alanasi. Chaos and fractals in dynamical models of transport and reaction. A difference in the 6PGDH zymogram pattern between the two species with respect to this chromosome has been noted. The idea of moving parts of the health care process from expensive specialised hospital care to primary health care and home health care might be attractive in a cost perspective. In contrast, only MUC1 levels increased with no significant changes in expression of MUC5B and MUC8 in cervical tumors over normal cervical tissues. The formation of immunocomplexes resulted in fluorescence resonance energy transfer from the CdTe quantum dot donors to the TRITC acceptors. All of the 28 implants placed in combination with sinus membrane elevation were stable during the first year of loading. The preferential habitat and trophic level of the component species have been assessed from the signature of stable isotopes (delta13C and delta15N).

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