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Alpra (Alprazolam)

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Alpra is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpra, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpra is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aleez, Alflux, Almac, Alpaz, Alpracon, Alpram, Alpraquil, Alprasan, Alprasert, Alprastan, Alprogard, Alprozam, Alwe, Alzom, Alzopax, Anquil, Anxiflu, Anxigo, Anxizam, Azicalm, Benzax, Deproz, Depser, Elzopam, Esteem, Fluprax, Fluzolam, Himzolam, Nitril, Ozolam, Plxna, Poize, Pranol, Resolin, Resto, Serex, Silam, Somaspas, Sowel, Synozolam, Tenlax, Xycalm, Ziety, Zolar, Zopain, Zorest

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Alpra exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Alpra in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Alpra may be habit-forming. Never share Alpra with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Alpra extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Alpra suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.


If you have been prescribed Alpra for medical reasons, the best way to avoid a Alpra overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpra consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpra XR dosage information

Side effects

The most common side effects associated with Alpra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Recovery potentials following CNS lesions: a brief historical perspective in relation to modern research data on neuroplasticity. Adenovirus genes required for the elicitation of adenovirus group C-specific cytolytic T lymphocytes (CTLs) and for the induction of adenovirus-specific transplantation antigen (TSTA) were identified by immunization with a library of adenovirus mutants. The first ophthalmologists came to Australia from Great Britain in the early 1860s and founded charitable eye hospitals on the British pattern. Chemotherapy for disseminated disease generally gives disappointing results, since only a minority of tumors respond and survival benefit is marginal. It was found that the chirp length can be increased and bandwidth reduced to improve SNR, though resolution is sacrificed.

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Ankyrin and the hemolytic anemia mutation, nb, map to mouse chromosome 8: presence of the nb allele is associated with a truncated erythrocyte ankyrin. Content represented managed care and non-managed care topics in varying proportions. Home parenteral nutrition and indications for small-bowel transplantation. Genotypes were determined through polymerase chain reaction with or without restriction fragment digestion. Subjects were randomly assigned to one of two conditions: 13 received the CSTP to increase their hypnotic susceptibility, and 14 received no training. The mesio-distal diameter in TS patients was significantly reduced for every tooth measured (in particular for the lower first permanent molar). S100A7 (Psoriasin)--mechanism of antibacterial action in wounds. Simultaneous prescription of digoxin and an anti-arrhythmia agent, is it dangerous?. Expression of c-fos protein by N-methyl-D-aspartic acid in hypothalamus of immature female rats: blockade by MK-801 or neonatal treatment with monosodium glutamate. After that the activity was detected at wavelengths of 313 and 492 nm using a layer thickness of 10 mm.

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Recombinant adenovirus AdHT-rev-casp3 expressing rev-caspase-3 driven by hTERTp effectively causes cell apoptosis targeting tumor, significantly suppresses tumor growth and prolongs the mouse survival duration, with mild liver toxicity. The radioreceptor assay (RRA) was used to quantitate plasma triazolam concentrations in eight female volunteers following single 0.5 mg doses of two tablet formulations in a cross-over study. In this paper, we propose a new feature extraction method for feedforward neural networks. Previous studies have demonstrated that the LUS thickness measured sonographically has a high negative predictive value for uterine rupture, suggesting that a normal LUS thickness predicts a safe trial of vaginal birth after previous Caesarean section (VBAC). Understanding implicit and explicit attitude change: a systems of reasoning analysis. This seems to be the first documentation of adenosquamous carcinoma of the liver invading the esophago-gastric junction. This article estimates the incremental cost to hospitals of swing-bed care and assesses the adequacy of swing-bed reimbursement in light of those estimates.

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Sustained hypotension and poor organ blood flow are associated with brain injury including peri/intraventricular haemorrhage and subsequent poor neurodevelopmental outcomes. Using FRET to measure the angle at which a protein bends DNA: TBP binding a TATA box as a model system. Unilateral chronic moderately elevated IOP was produced in rats by cautery of three episcleral vessels. The difference is that our patients are seen when lesions are very advanced and all therapeutic measures do not get five years survivals. Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivation and the possible pathogenetic role of the Epstein-Barr virus. One patient died preoperatively and postmortem examination confirmed the color flow diagnosis. Recent studies, predominantly using the mouse 3T3-L1 pre-adipocyte cell culture model, have shown that the role of vitamin D in inhibiting adipogenesis is mediated at the molecular level through a vitamin D receptor (VDR)-dependent inhibition of CCAAT enhancer binding protein-alpha (C/EBP alpha) and peroxisome proliferator-activated receptor-gamma (PPAR gamma) expression and a decrease in PPAR gamma transactivating activity in the pre-adipocyte.

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However, consistent with physical changes in adulthood, current and ideal ratings became more discrepant with age. The author uses the additional 3-0 prolene suture on the gastrojejunostomy, but his associate does not. Cultural responses to same-sex sexuality led to the spread of exclusive homosexual behavior and to the creation of a homosexual identity. Peak plasma glucose was observed at 15 min after exercise, and peak heart rate and VO2 were recorded at highest speed during SET. The use RGP contact lenses greatly reduced total aberration of the anterior surface of the cornea. Contact urticaria caused by Obeche wood (Triplochiton scleroxylon). Its theoretical foundation as a social science was laid by Alfred Grotjahn in the years before 1914. Additionally, we demonstrate that this technique can also be applied to freely suspended graphene resulting in freely suspended graphene nanoribbons. In both cases, after months of symptoms, persistent norovirus infection--documented by repeatedly-positive high-sensitivity stool enzyme immunoassay--was found to be the cause.

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Encapsulated intracerebral hematoma is an interesting and not widely appreciated entity. The recovery of blood-nerve barrier in crush nerve injury--a quantitative analysis utilizing immunohistochemistry. Many real images are made up of both smooth and textured regions and are best segmented using different features in different areas. Similar bimodal rhythms were induced by exposing freshly captured crabs, with free-running circatidal rhythms, to tidal antiphase cycles of each of the three environmental variables applied individually. In the absence of rapid, simple and sufficiently sensitive methods for the direct detection of prion in commercially slaughtered animals, marked organisms can provide useful models in studies of the dissemination kinetics of prion disease in captive bolt stunned animals. Adults who had been exposed to parental problem drinking in childhood were more likely to manifest psychiatric symptoms and marital instability, but they showed no difference from the rest of the sample in occupational functioning. In both regards studies in tissues or cells natively expressing the subtypes are hampered because the relative expression of the subtypes is poorly controlled and the observed effects may be cell-type specific.

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In vitro activity of lysostaphin, mupirocin, and tea tree oil against clinical methicillin-resistant Staphylococcus aureus. However, when given with the pancreatic secretagogue cholecystokinin, each altered the effect of injection of cholecystokinin. Effects of biomimetic surfaces and oxygen tension on redifferentiation of passaged human fibrochondrocytes in 2D and 3D cultures. Three types of changes in neuronal reaction pattern were identified during differential conditioned stimulus compared to the pattern observed during positive conditioned stimulus. Case history and hospitalization factors in suicides buy zovirax cream online of neuropsychiatric hospital patients. In each case two-stage operations were undertaken with excellent results.(ABSTRACT TRUNCATED AT 250 WORDS). Induction of nuclear protein factors specific for hormone-responsive region during activation of thyroglobulin gene by thyrotropin in rat thyroid FRTL-5 cells.

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Primary biliary cirrhosis and IgG-kappa type multiple myeloma both respond well to vincristine, adriamycin and dexamethasone: is there a pathogenic relationship?. Phase 1 of the Trials of Hypertension Prevention was a collaborative, randomized controlled clinical trial designed to determine the feasibility and efficacy of selected nonpharmacologic interventions in reducing or preventing an increase in diastolic blood pressure. In this article, we present a brief overview of two culturally relevant conceptual tools: a) the Cultural Formulation Model, and b) the Multicultural Case Conceptualization approach. Effect of granulocytopenia on oral microbial relationships in patients with acute leukemia. Eight strain gauges were attached to the buccal and distal surfaces of all implants. Solving the scattering problem, we show that the attraction in the exotic channels is not strong enough to generate a bound state. Surprisingly, these dominant negative mutants of Rex and Rev fail to interact in vivo. In addition, dominant-positive HSF1 acquires transcriptional zebeta 5 mg cost activity, which dominant-negative HSF1 does not acquire.

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Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis. This plant has been increasingly used for making floral decorations during the last decade. Human papillomavirus (HPV) types 16 and 18 are known to play a major role in cervical carcinogenesis. Moreover, a combination of CPT-11 and MMC exhibited the highest anti-tumor activity in this animal model. Immunohistochemistry confirmed increased amyloid precursor-like protein 1 protein expression and revealed the presence of diffuse Abeta plaques in Mn-exposed frontal cortex. Epinephrine-induced desensitization was rapid in onset, with a maximum decrease in responsiveness 6 h after treatment and responsiveness returning to control levels within 24 h of treatment. 12 healthy adult German Shepherd Dogs and data previously collected from 16 healthy adult Labrador Retrievers. Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences. Two forms (I and dulcolax stool softener liquid gels dosage II) with acidic pH optima and a neutral form of beta-hexosaminidase has been separated by DEAE-cellulose chromatography and characterized in skin and lung of 7, 9, 11, 14 day chick embryos and 1 day old chicken. Natural infection of the Glossina caliginea in the Douala mangrove swamps, Cameroons.

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There was a modest decline in stroke incidence in women (overall and for New Zealand European women in particular) in Auckland over the past 20 years but there also was a trend towards increasing stroke incidence in Maori, Pacific, and Asian women. An analysis of an MRSA outbreak in a geriatric institution showed a collection of genetically homogeneous isolates. Comment on modern blood vessel surgery with continuation of blood flow. Clonidine (2.5 micrograms/kg body weight, iv) induced GH elevations that were not significantly different between patients and controls. The veno-occlusive mechanism of the corpora cavernosa was studied directly by determination of flow along the deep dorsal vein of the penis and indirectly by serial evaluation of the diastolic flow of the cavernous can a minor buy zyrtec arteries. In order to extend its success in internal medicine into neurology, it was necessary to provide a paradigm for neuroanatomic reasoning. Structure of the gene coding for the human retinoic acid-inducible factor, MK. COOH-terminal processing is proposed to ensure a correct sequence of events for assembly of the 32-kilodalton protein into the photosynthetic membrane. Further activities for domestic nursing personnel and medical doctors were introduced successfully.

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Basic and rulide 300 mg clinical studies on the effect of cefmetazole on infection in gyneco-obstetrics. Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor. We find that the neocortex is randomly divided into diffused bands, the majority of cells within each band have the same colour, and their radial orientation suggests radial dispersion. Some patients (those with mutations in KCNJ11 and ABCC8) may be transferred from insulin therapy to sulphonylureas. When compared with the control group, there was no difference in the percentage of PMNs infected with Leishmania or in the number of amastigotes/100 PMNs in HTLV-1-infected individuals. We use a new, easily computed distance that successfully eliminates most codewords from consideration. The purpose of this study was to design and evaluate hirudin (HIR) derivatives with low bleeding risk. Temperature sensitive radio transmitters were implanted into the abdominal cavities of two substrains of pointer dogs to monitor the core temperature during a 12:12 L/D cycle. These results demonstrate that the structural conformation of ATF-2 is critical for DNA binding and protein-protein interactions and, further, that leucine zippers can mediate protein-protein interactions with structural motifs other than leucine zippers. Furthermore, the concentration of serum in the culture medium must be transiently reduced during the transfection.

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We distinguish two spatially distinct fibroblast populations expressing different connexins: fibroblasts surrounded by other fibroblasts preferentially express connexin40, whereas fibroblasts that are intermingled with myocytes largely express connexin45. SP had no effects on epithelial cells following stimulation of mast cells. The level of habitual protein intake influences postexercise skeletal-muscle protein turnover. The trained listeners practiced asynchrony detection in one experiment and order discrimination in the other. The appearance of these factors may reflect important common elements in the complex series of cellular changes occurring in response to acute brain injury. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer. It is possible to identify probably benign breast masses using gray-scale sonography, and thereby to reduce the number of biopsies performed. Venous thromboembolysm denotes high risk of subsequent myocardial infarction and stroke: results of large population study. Within a factor of 10, pH was independent of the number of FSP added to macrophages in vitro. Clinical and radiographic indices associated with airflow limitation in patients with sarcoidosis.

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