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Alpracon (Alprazolam)
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Alpracon

Alpracon is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpracon, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpracon is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Almac, Alprac, Alprine, Alprogard, Alrif, Alzolam, Andep, Anilam, Anquil, Anxit, Anxofit, Anzocalm, Ateez, Axnil, Berest, Dazolam, Destres, Dexolam, Diprex, Elzopam, Emlol, Endolam, Esteem, Golprax, Mentolift, Nitril, Pacyl, Poize, Pronext, Prosanti, Rezolam, Serex, Sertamax, Setlan, Sinzolam, Somaspas, Tenfree, Tenolam, Tenschem, Xylonite, Zolipax

Similar Products:
Elavil, Persantine, Bactrim, Klonopin, Fasigyn, Prometrium, Nimotop, Alprostadil, Lozol, Metronidazols, Levoquin, Amodipin, Riomet, Glimiprex, Domase, Sildenafil, Uricin,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpracon dosage information

Overdose

If you have been prescribed Alpracon for medical reasons, the best way to avoid a Alpracon overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpracon consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpracon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Grapefruit may interact with alprazolam and lead to unwanted side effects. Avoid the use of grapefruit products.

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These plasmids were identical in mobility on agarose gels and exhibited the same restriction patterns as the native pRUT41 plasmid isolated from Z. The database is accessible on the web at http://monod.biomath.nyu.edu/rna. Lipopolysaccharide restores anti-Candida albicans growth inhibition activity of polymorphonuclear neutrophils from retrovirus-immunosuppressed mice. Identification of the skin basement-membrane autoantigen in epidermolysis bullosa acquisita. It is becoming increasingly evident that clinicians should be more discriminating when making therapeutic decisions for persons with COAD. Thus a pan-symptomatic group, with high scores on all four dimensions, ranks highest in overall treatment difficulty. The amounts of HBsAg and nucleocapsid protein in culture medium were roughly related to the number of viable cells. Large foreign body as a nidus for a common duct stone in a patient without spontaneous biliary enteric fistula or previous abdominal surgery. Silencing tjp3/zo-3 using morpholinos leads to edema, loss of blood circulation and tail fin malformations in the embryos.

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Four ABC specimens of metastatic prostatic carcinoma were diffusely positive. Effects of ionizing radiation on wildlife: what knowledge have we gained between the Chernobyl and Fukushima accidents?. Human implantation: the last barrier in assisted reproduction technologies?. Multiple space-taking processes in cerebral roentgenography, with special reference to ventriculography. The external membrane of the endocytic vesicles apposes that of the food vacuole, leading to the internalization of vesicles bounded by a single membrane into the vacuole space where they are rapidly degraded. No significant changes in cerebral cortex cAMP concentration were observed in the same experimental conditions. Chromatography of the soluble porcine lymphocyte phospholipase C on cellulose phosphate resolves the activity into two species. This decrease was associated with a significant decrease in androgen receptor and IL-12 mRNA expression in PCO splenocytes. Addition of exogenous histone H1 to isolated calf thymus mononucleosomes in low ionic strength buffer resulted in the formation of electrophoretically distinct mononucleosome assemblies (supernucleosomes).

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In conclusion, our study has shown that brushing with fluoridated water has a positive effect on the fluoride level of the plaque and the addition of MFP did not make a significant change, although it had a short term effect. This position of GalUA is exceptional as compared with the terminal constituents present in the known structures of R core polysaccharides in Enterobacteriaceae. Hence, it remained unknown why CagA is constantly phosphorylated in sustained H. Errors were computed for the peak positive and negative pressures, risetime, pulse duration, and pulse intensity integral as functions of hydrophone and amplifier bandwidths. Effect of alpha- and gamma-tocopherol as well as cholesterol on lipid peroxidation.

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It is concluded that the energy barrier for the oxidation of zinc fingers is strictly dependent on the type of ligands coordinated to zinc and on the protonation state of the complex. Simulated diseases in malingerens (observed in military hospitals). We devised a residue-specific, protein backbone move set for efficient sampling of protein-like conformations in computational folding simulations. Results indicate that none of the subjects are training residents at their pain practice and the majority are not training pain fellows. If it were possible to select patients with sensitive tumor cells to this agent by the MTT assay, the phase II trial might be completed within a short period by reducing the number of studied patients. Oxidized T4 lysozyme (Ile3----Cys) exhibited specific activity identical to that of the wild-type enzyme when measured at 20 degrees C in a cell-clearing assay. The etiology of this possible survival advantage is currently unknown. In non-responders these tendencies were much less pronounced or absent.

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Drugs which increased smooth muscle tone improved peristalsis and, under the conditions used, they reduced flow. One test was given 2 hr and a second 24 hr after the termination of the operant task. The understanding of cellular response to the shape of their environment would be of benefit in the development of artificial extracellular environments for potential use in the production of biomimetic surfaces. Organocatalytic asymmetric michael addition of aldehydes to beta-nitroacroleine dimethyl acetal. There is a good correlation in calculating EF by LVG, QGS and echocardiography, regardless of EF value. A clinical study on oral radiogenic complications in tumor therapy in the head-neck area. We show both numerically and experimentally that through appropriately selecting the output coupling position and strength in a mode-locked fiber laser, one can effectively manage the nonlinearity of the cavity. Systemic administration of dopamine D1 or D2 receptor antagonists to rodents prevents mAMPH-induced damage to striatal dopamine nerve terminals.

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Immunohistochemistry was performed with antibodies specific for cytokeratin 8 and 18 (CAM5.2), GH, prolactin and E-cadherin. Microsurgical anatomy for lateral approaches to the foramen magnum, especially for transcondylar fossa (supracondylar transjugular tubercle) approach, was studied using cadavers. Uterine weight reached a maximal sixfold increase 48 h after injection of CT. A systematic MEDLINE review was conducted to identify reports of hepatectomy outcome between January 1998-December 2004. However, about 1 year and 6 months later, the patient was diagnosed as having recurrent endometrial carcinoma in the left external iliac lymph node. Our understanding of prokaryote-eukaryote symbioses as a source of evolutionary innovation has been rapidly increased by the advent of genomics, which has made possible the biological study of uncultivable endosymbionts. The preferential stimulation of ASIF production is revealed by the combined treatment rendering the ASIF to ANF proportion similar to that in brain. Respiratory symptoms were more common in cases, although the differences were not statistically significant. As is demonstrated, higher quality is achieved at lower bit rates. Alveolar leukocytes from patients with inflammatory lung diseases and nonsteroid treated lung cancer responded better to the interferon inducers than did cells from other patients.

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The effects of nicotinamide (NIC) and selenium (SE), given alone or together, on N-nitrosobis (2-oxopropyl) amine (BOP)-induced DNA damage were measured in rat liver and colon. New cytotoxic saturated and unsaturated cyclohexanones from Anthemis maritima. Effects of atrial natriuretic peptide on left ventricular function in man. The addition of morphine 0.1 mg/kg to the local anesthetic axillary block solution provided improved postoperative analgesia without an increased frequency of side effects or major complications. Apolipoprotein B has previously been thought to be a homogeneous protein. An emerging role for a cardiac peptide hormone in fish osmoregulation. The increase in muscular venous PCO2 may enhance the myocyte permeability to lactic acid during exercise. Subclinical abortion does not contribute to the contraceptive effect. Blood concentrations of this antibiotic were determined in clinically ill snakes following an intramuscular injection at a dose rate of 20 mg kg-1.

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The author reports on the problems of preparing and anaesthetizing patients in 204 prostatic operations made in 1983 at the Department of Urology of the Postgraduate Medical Institute, Budapest. Primary hyperlipoproteinemia in its clinical and laboratory aspects. Earlier research suggested that the task was sensitive to drugs and pathology. In only one case did the pairwise analysis suggest the simulated order, indicating the necessity for multi-locus analysis for gene order. A blended learning experience that combines traditional practices and e-learning was implemented to teach microbiological methods to pharmacy students. Gender and inter-species influence on coagulation tests of rats and mice.

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Infection is then carried through the efferent fibers of the post-ganglionic neurons of the parasympathetic and sympathetic nervous system to the pre-ganglionic neurons in the medulla oblongata of the brain and the thoracic segments of the spinal cord. The purpose of this study was to review the literature concerning the risk factors for cancerous and precancerous lesions of the biliary tract, and prophylactic surgery for these factors. Western analyses demonstrated cellular secretion of lipocortin into the medium. Anti-endothelial cell antibody and immune complexes in the sera of animals with acute experimental allergic encephalomyelitis and chronic relapsing experimental allergic encephalomyelitis. Acute necrotizing retinitis following varicella zoster virus infection. The identification of prognostic factors associated with engraftment that can be easily modified (e.g., strategies for donor choice) and the development of new approaches including use of multiple donors, intrabone injection of UCB, ex vivo expansion, and cotransplantation with accessory cells are of crucial importance in order to circumvent the problem of delayed engraftment after UCB transplantation. The presence of these auxiliary proteins could underlie some of the unusual aspects of kainate receptor function in the mammalian CNS. For the further improvement of local recurrence-free survival of patients with myxofibrosarcoma, accurate diagnosis of the tumor extension and adequate planning for the surgical margin should be focused on in cases with bone and/or joint attachment. The difference in inhibitory action appears to depend on the categorized subclass of flavonoids. Expression of HER2 is associated with clinicopathological features in the gastroesophageal cancer.

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Anteroventral cochlear nucleus: wave forms of extracellularly recorded spike potentials. Extracellular bacteria, including those adherent to the phagocytic cell surface, can do so however. Furthermore, on the basis of the terminal transfer model, anomalous patterns of Y sequences are evident in certain XX males in that sequences located as proximal Yp by means of a Y deletion panel are found to be present in the absence of distal sequences. The granulosa/luteal cells obtained on the day of oocyte retrieval after GnRH agonist trigger are still viable and have the capacity to respond to hCG by increasing the secretion of steroids. This crevice is adjacent to the non-overlapping ganglioside-binding site of BoNT/B. 2 cases of gastric-cancer remarkably reduced with a combined dosage of irsogladine maleate preparation and uft. It was found out that the developmental transformations of the testicular veins, initiated in the embryo, progress very dynamically in foetuses up to about the 20th week of pregnancy and them gradually slow down in older foetuses.

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hVDR competed with hCAR for the hSULT2A1 promoter in Caco-2 cells. These changes in ventricular function have been found to be reversible and the clinical data are consistent with the occurrence of myocardial stunning. In no instance was there any preceding breakdown of overlying skin. Acclimation to sublethal acidic and alkaline media of Tilapia mossambica (Peters): changes in glycogen metabolism of red muscle. The predictor consists of an adaptive linear element (Adaline) followed by a multilayer perceptron (MLP). Measurements of leakage of each sample were obtained at 24-hour intervals for 30 days. Two of the patients had multiple hepatic abscesses, one had hepatic, intra-abdominal and intrapelvic abscesses, and one had an intrapelvic abscess alone. End point staining of cells or viability stains are reliable but they are often not sensitive enough or not suitable for automation. Although controlled costs of the health care system may be an important goal for society as a whole, the individual patient is seldom satisfied with being an object of health care rationing.

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There is no question about their part not only in the establishment of medical care structures in Palestine as well as the design and diversification of the Israeli health care system, but also in the international significance of Israeli developments in medicine and life sciences in the second half of the twentieth century. Three of the lobes form a roughly triangular base with a central channel approximately 20 A in diameter. The mean-square displacement displays anomalous transport, which extends to infinite times precisely at the critical obstacle density. Pre-hospital intubation is associated with increased mortality after traumatic brain injury. Intraoperative transesophageal echocardiography in a patient with persistent left superior vena cava syndrome. The discrepancy between the studies may be caused by the large variation in experimental set-up. Shrinkage of growing Escherichia coli cells by osmotic challenge. Carbon dioxide laser treatment resulted is cosmetically acceptable healing without recurrence. Cognitive-behaviour therapy is one of the evidence-based psychotherapies that have been successfully applied to the treatment of patients with psychotic symptoms.

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Randomised controlled studies (RCTs) in patients with CHD with a minimum follow-up of 6 months. Nephrectomy resulted in cure of medically unmanageable hypertension. It is shown that a principal feature of the design process and subsequent assessment of the system is the way in which modelling of processes, mechanisms or functions provides a common focus for establishing the important criteria for system design and evaluation of its applicability. Cefamandole alone or in combination with tobramycin appears to be an effective and safe antibiotic when used in appropriate doses for the treatment of bacterial peritonitis. Proper timing of the floral transition is regulated by different pathways and is critical for the reproductive success of plants.

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Simvastatin treatment improved the expression of mRNA for LXRalpha, ABCA1, and ApoA-I compared with DMHL or control groups. Screening for early familial ovarian cancer with transvaginal ultrasonography and colour blood flow imaging. Oral implications associated with CF include enamel hypoplasia and tooth discoloration, salivary gland involvement, reduced incidence of dental caries, reservoir for potentially pathogenic respiratory bacteria, mouth breathing, and anterior open bite associated with nasal and sinus obstruction. Diagnosis of isolated sphenoid sinusitis was made after ENT and radiological examination. A direct comparison of the molecular mass of the Mu-IFN-gamma receptor on intact cells versus detergent-solubilized membranes was performed using a radiolabeled photoactivated crosslinking reagent and direct hybridization with 125I-labeled IFN-gamma on Western blots of solubilized receptor.

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The present study examined whether aripiprazole modifies the behavioral and physiological effects of a moderate dose of alcohol in a group of social drinkers. After treatment with MPA, the PR content was reduced and histological appearance similar to normal endometrium was noticed. The ts phenotype was manifested as a loss of cell binding, reduced replication, and virions that were lacking surface HN after growth at the nonpermissive temperature (38 degrees). Hence, both on non-governmental and governmental levels--represented in this synopsis by the Federal German Association for Health Education and the Dortmund Public Health Service--model initiatives for the intensification of health education are translated into reality. Patients without overt neurological symptoms exhibited intrathecal synthesis of anti-HIV-1 IgG as often as those with such symptoms. So far, follow up of the 14 patients with cystic adenoma and the 19 patients with teratoma, has shown no recurrence of tumor in the remaining ovary. Precore defective HBV mutant has been suggested to be responsible for the pathogenesis of fulminant hepatitis. The regulatory, informational, and immunomodulatory roles of fat fuels. Intestinal shock was created by occluding both superior mesenteric artery and vein in the two groups.

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Need for hospice approach to treatment of patients with advanced progressive dementia. Water quality modeling of fertilizer management impacts on nitrate losses in tile drains at the field scale. The resulting cells are devoid of both the 3.6-kb DMIHC gene transcript and the 124-kD DMIHC polypeptide. Intervention students also reported lower intentions to use alcohol and tobacco, less alcohol and tobacco use initiated during the study and in the past 30 days, and reduced levels of aggression. The number of admissions per day, service level and occupancy level are key control parameters that affect the optimum size of the required bed capacity. To observe clinical therapeutic effect of monkshood cake-separated mild-warm moxibustion at Zusanli (ST 36) and Xiyan (EX-LE 5) on knee osteoarthritis. In this manner nystatin and triamcinolone acetonide yeast infection , the Cy5.5 fluorescence will be inhibited everywhere but in the target. Changes in medico-ethical and deontologic concepts in the field of gynecology in first 1/3 of the 20th century.

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Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes. Such interactions might be inhibited by synthetic peptide probes derived from the cell-binding regions of matrix molecules. An increasing number albendazole brand of biochemistry and biotechnology graduates are finding work in industry in the area of industrial validation associated with biopharmaceutical, diagnostics, biomedical device, and pharmaceutical validation. Newer techniques including ultrasonication and molecular diagnostic studies are playing an expanded role. A subsequent prospective investigation with serial radiography demonstrated healing approximately twelve months after a changed treatment regime. Synovial osteochondromatosis of the second metatarsophalangeal joint: a case report. The proposed methods are based on the maximum likelihood estimates. Effects of the amount of valgus correction for medial compartment knee osteoarthritis on clinical outcome, knee kinetics and muscle co-contraction after opening wedge high tibial osteotomy. Gel-shift analysis reveals the constitutive presence of nuclear factors in resting PBL that bind to the proximal AP-1 site of the IL-2 promoter and that contain immunoreactive c-Jun but not c-Fos protein.

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In this study the authors conferred the progesterone, DHAS, cortisol, oestradiol, oestriol, prolactin and HPL levels of male and female newborns in the maternal vein and in the umbilical vein and artery in the 28th-32th weeks (31 parturients, 15 male and 16 female fetuses), in the 33rd-36th weeks (43 parturients, 20 male and 23 female fetuses) and in the 40th week (34 parturients, 11 male and 23 female fetuses) of pregnancy. Antigen-specific T-lymphocyte function after cord blood transplantation. These findings could be quantitatively accounted for by a model encompassing the kinetics of the individual activation and inhibition steps. The association state of the purified enzyme has been found to depend on pH and ionic strength. Adults with CF, at least in the West Midlands, have poor knowledge of the risk and consequences of cross-infection.

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Affective disorders in motor neuron disease: a population-based study. In experiment 1, oocytes were cryopreserved and evaluated for survival on the basis of morphologic criteria. Relapsing granulomatous angiitis of the central nervous system in a patient while in remission from Hodgkin lymphoma. There are deficits in the implementation and adherence to evidence-based guidelines for managing chest pain in hospitals across Australia, and significant differences between hospitals with and without interventional facilities. Lung transplantation is considered a new and promising therapeutic mode for treating patients with end-stage pulmonary failure related to fibrosis, emphysema, infective conditions, and pulmonary hypertension yielding satisfactory early results. Mistakes, misidentification, or willful deception can cause illness and even death. The mRNA levels increased in the liver and spleen but not in the kidney after administration of carbon tetrachloride. Presentation of a latex test for the research on anti-myocardial antibodies.

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