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Alpram (Alprazolam)

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Alpram is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpram, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpram is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpram, Alprawin, Alprop, Alrif, Alzoact, Anilam, Anxiflu, Anzilum, Anzocalm, Betapax, Endep, Esteem, Fluwel, Hipose, Mediprex, Mentolift, Morecalm, Norex, Notence, Notens, Paxor, Propnix, Resto, Rezolam, Richpram, Samprex, Tenscure, Tensyl, Texidep, Tranax, Tranisol, Xycalm, Zoldac, Zopam

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Crestor, Prilosec, Myambutol, Caverta, Retin, Duphaston, Zyloprim, Propecia, Nimotop, Ovipreg, Diamet, Famit, Atenerate, Hypodehydra,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpram dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpram XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpram dosage information

Side effects

The most common side effects associated with Alpram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells. Antheminones A and C exhibited significant antiproliferative activity against leukemia cells with IC(50) values ranging from 3.2 to 14 microM. Aspirin has been reported to induce the adult respiratory distress syndrome (ARDS) in humans. Biological and immunological properties of Sugi basic protein-pullulan conjugate. A flat revertant cell line which expresses a biologically functional E1a but not the transformed phenotype was nevertheless susceptible to TNF. The lack of a thioesterase domain in GliP may account both for the slow release and for the directed fate of intramolecular cyclization to create the DKP scaffold for subsequent elaboration to gliotoxin. The oxytocin-induced excitation was suppressed by a synthetic structural analogue that acts as a potent, selective antioxytocic on peripheral receptors. rab9 is a ras-like GTPase which has been implicated in the transport of mannose 6-phosphate receptors between late endosomes and the trans Golgi network. Spinal pain, especially chronic low-back pain is one of the most prominent health and healthcare problems. Experience in the application of pramistar, a new nootropic preparation, in the treatment of memory disorders in patients with cerebrovascular pathology.

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Gender and ethnic differences in a case-control study of dyslipidemia: using the apolipoprotein A-V gene as an exemplar in cardiovascular genetics. The highest Pi absorption rates were found in anaerobically grown seedlings under anaerobic (32)P-uptake conditions. Fracture of the body of the hamate bone associated with compartment syndrome and dorsal decompression of the carpal tunnel. A comparison of the phosphorylated and unphosphorylated forms of isocitrate dehydrogenase from Escherichia coli ML308. 1-second value and oscillatory airway resistance in the evaluation of the effectiveness of beta-adrenergic agents under general practice conditions. A mechanistic study of the essential allosteric activation of human pancreatic alpha-amylase by chloride ion has been conducted by exploring a wide range of anion substitutions through kinetic and structural experiments. The chromosome on which initiation occurs is the recipient of genetic information during gene conversion. However, low fracture toughness and linear elastic behavior demonstrated by ceramic make it prone to breakage under stress. Raised serum copper and caeruloplasmin levels in subjects taking oral contraceptives.

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Experimental use of high-frequency ultrasound to image bowel wall after porcine intestinal transplantation. A total of 140 laparoscopic Roux-en-Y gastric bypass (LRYGB) procedures have been performed with robotic assistance (80 with Zeus and 60 with da Vinci). To investigate the potential source of ongoing oxidative processes, we show increased levels of 3-nitrotyrosine, a phenergan and codeine cough syrup marker of damaging nitrogen/oxygen species in macrophages. The basic research design included a cross-sectional study involving a random probability sample of 3000 UK residents. In the TBI group, better executive performance was related to the use of problem focused coping (considered more adaptive). To address this problem, we have developed an agglomerative clustering method that is able to identify highly modular sets of gene products within highly interconnected molecular interaction networks. Spermatozoa from several other mammalian species were also found to express this antigen, suggesting its evolutionary conservation across the species. We engineered a mouse Mphi cell line to express the murine interferon-gamma (IFNgamma) under the control of an inducible promoter containing the hypoxia-responsive element, which can be triggered by hypoxia and other stimuli. The hemodynamic effects of intravenous class I and class IV antiarrhythmic drugs were investigated at different doses in comparison.

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