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Alprazolam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Alprocalm, Alprop, Alprosym, Alprotame, Alzopam, Anxicalm, Anxiflu, Betapax, Calmef, Esteem, Exiten, Finezol, Fledore, Fluzolam, Mentolift, Morecalm, Nucalm, Parazolam, Selamb, Silam, Sinozol, Texidep, Xylonite, Zedep, Zeecam, Zeftra, Zolam, Zopain

Similar Products:
Furadantin, Maxolon, Amoxil, Imovane, Flonase, Claromycin, Orgamed, Meriben, Zonap, Alpose, Kefurox, Norflogen,


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alprazolam dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazolam XR dosage information

Side effects

The most common side effects associated with Alprazolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Grapefruit may interact with alprazolam and lead to unwanted side effects. Avoid the use of grapefruit products.

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Development of international cooperation in the field of cancer research. A total of 103 patients with primary open angle glaucoma were included. Thus, in this series, leukaemic relapse was not found occurring in donor cells. Recent phase I/II trials report encouraging results in selected patients with peritoneal mesothelioma (PM) treated with cytoreductive surgery (CRS) and intraperitoneal hyperthermic perfusion (IPHP). Streptococci produce a variety of protein toxins and enzymes that are capable of killing host cells and breaking down cell constituents, presumably to provide nutrients for the bacteria or to promote their spread.

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We conclude that this major serratial exoprotease has a deleterious effect on mice infected with influenza virus and that this effect seems to result from enhancement of viral growth by indirect acceleration of plasmin generation induced by the protease. Perhaps CD is under-reported and a high proportion of patients remain undiagnosed. Murine endogenous IL-12 p40 mRNA was consistently induced by overexpressed EKLF in resting RAW264.7 cells, whereas EKLF suppressed IL-12 p40 expression in activated RAW264.7 cells. 25 years after reconstruction of an aortic coarctation by prosthetic material, an insufficiency of the anastomosis gave rise to the development of a false aneurysm. Periods between 4 and 26 months had passed from surgical treatment or beginning of conservative therapy at the time of the follow-up check. Studies on insects resistant to the insecticide imidacloprid and on laboratory-generated hybrid and chimaeric nACh receptors in vitro have provided information about the molecular basis of receptor diversity, neonicotinoid resistance and selectivity. The EL4 lymphoma in C57BL/6 mice was used as a model to examine the effect of progressive tumor growth on a variety of cell mediated cytolytic effector functions which have been shown in other systems to have antitumor potential.

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A forced global alignment between a contig and the reference is not only time consuming but often meaningless. Patient demographics, Injury Severity Score, and survival past 24 hours were recorded. Barbiturate protection against hypoxic neuronal damage in vitro. Hence the use of non-ionic contrast media is associated with less undesirable side-effects that are attributable to hypertonicity such as an increase in circulating plasma volume, decreased deformability of red blood cells, damage of vascular endothelium with consequent activation of blood coagulation, the complement system and fibrinolysis, increased release of bradykinin and histamine, cardiac arrhythmias, diuresis, vasodilation and decreased blood pressure, pain and heat sensation. Urinary levels of immunoreactive NH2-terminal of pro-opiomelanocortin in patients with malignant pulmonary disease.

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Fumonisins are carcinogenic mycotoxins produced by the maize ear rot pathogen Gibberella moniliformis (anamorph Fusarium verticillioides). This article describes the development of an advanced system of vE for endoscopic transsphenoidal pituitary surgery and its application to teaching, training, and in the routine clinical setting. Daily intakes were specifically determined for a standard adult of 70kg, and compared with the tolerable/admissible intakes of the pollutants, if available. However, recent findings demonstrate that activity plays essential roles in early development of the nervous system. Pretreatment, cotreatment, and posttreatment with electrolyzed-reduced water enhanced human lymphocyte resistance to the DNA strand breaks induced by H2O2 in vitro.

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Our results do not agree with previous suggestions that hemoglobin-mediated hepatotoxicity is due to the interaction in vivo of hemoglobin with low levels of endogenous endotoxin. Whereas molecular cloning experiments have provided evidence for the presence of two closely related genes for the catalytic subunit of the cAMP-dependent protein kinase, the possible interchangeability of these isoforms in initiating biological processes has not been examined. The findings support the view that p53 is involved in breast tumour biology, and suggest that its role may be complex. Influence of hydrofluoric acid on bonding strength at the porcelain-resin interface. Primary urethral carcinoma is rare, and the demographic correlates of its incidence have not been examined using population-based data. Physico-chemical properties and amino acid composition of a highly purified preparation of a specific estrogen-binding protein of the rat liver. Trends in the detection of substance transport processes in ground water in waste deposits using numerical models. We asked whether a similar effect would occur in the context of simulated vehicles in a visual virtual environment.

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Comparison was made between the intact normal knee and sequential unicompartmental how much does lamictal cost and total knee replacement. Advances in the diagnosis and surgical treatment of urologic-gynecologic complications. In cerebral palsy, imbalance of the invertor and evertor muscles can result in varus alignment of the foot. Heterogenic properties of clonal cell lines derived from canine mammary carcinomas and sensitivity to tamoxifen and doxorubicin. The results showed a significantly greater range of opening in experimental than in control subjects at 8 weeks but not for lateral excursions. Identification and immunolocalization by monoclonal antibody of NSP-5, a surface polypeptide of neural cells. Closed-loop glycemic control with a wearable artificial endocrine pancreas.

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Circulating endothelin in children with congenital heart disease. Uniform elimination pattern for glibenclamide in healthy Caucasian males. Abnormally banded chromosomal regions in doxorubicin-resistant B16-BL6 murine melanoma cells. No modification has been introduced in the standard Talairach head-holder, preserving its features of simplicity and versatility without need for introduction of new stereotactic methodologies or new computer programs. Preservation of regional and global left ventricular function by intracoronary infusion with oxygenated fluorocarbon emulsion Therox in dogs. These disease-associated mutations (DAMs) are known to occur predominantly in positions essential to the structure and function of the proteins.

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