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Apomatine (Metoclopramide)

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Apomatine injection is used to treat severe diabetic gastroparesis. The injection is also used to prevent nausea and vomiting caused by chemotherapy or surgery, or to aid in certain medical procedures involving the stomach or intestines.

Other names for this medication:
Actinorm, Apomatine, Cepar, Cerinorm, Copar, Cosmet, Donmet, Elinorm, Emenil, Emenorm, Gastonorm, Gastrinorm, Maxeron, Maxinorm, Megatech, Metadrate, Metajex, Metanorm, Metcon, Metochlopramide, Metocin, Metoclop, Metocontin, Metomit, Metoz, Molmet, Motil, Naushi, Nausifar, Pacimol, Paranorm, Perilan, Perinorm, Peripan, Peronorm, Promet, Propamid, Pymet, Reglan, Regurg, Rivnorm, Tomid, Vagonorm, Vominil, Vominorm, Vomitex, Vomitrac, Vomitran, Vomonil, Zerinorm

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Also known as: Metoclopramide


Generic Apomatine medication belongs to a class of drugs called quinolone antibiotics. Generic Apomatine works by stopping the growth of bacteria. Generic Apomatine should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections. Apomatine is also known as Norfloxacin, Norfloxacine, Apo-Norflox, Norflohexal, Roxin, Utinor. Generic name of Generic Apomatine is Norfloxacin. Brand name of Generic Apomatine is Apomatine.


This section provides information on the proper use of a number of products that contain isosorbide mononitrate. It may not be specific to Apomatine ER. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This form of nitrate is used to reduce the number of angina attacks over a long time. It will not relieve an attack that has already started because it works too slowly. The extended-release form gradually releases medicine to provide its effect for 8 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.

You should take this medicine first thing in the morning and follow the same schedule each day. This medicine works best if you have a "drug-free" period of time every day when you do not take it. Your doctor will schedule your doses during the day to allow for a drug-free time. Follow the schedule of dosing carefully so the medicine will work properly.

Swallow the extended-release tablet whole with a half glass of water. Do not split, crush, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For prevention of angina: For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Take the dose in the morning right after you wake up. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—20 milligrams (mg) two times a day. Take the first dose in the morning right after you wake up, and the second dose 7 hours later. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apomatine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Apomatine if you are allergic to fenofibrate, or if you have:

severe kidney disease (or if you are on dialysis); liver disease; or gallbladder disease.

Do not breast-feed while using this medicine, and for at least 5 days after your last dose.

To make sure Apomatine is safe for you, tell your doctor if you have ever had:

kidney disease; liver disease; or gallbladder problems.

Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease, diabetes, or poorly controlled hypothyroidism (underactive thyroid).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Apomatine is not approved for use by anyone younger than 18 years old.

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