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Trisolvat (Trimethoprim)

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Trisolvat (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, including cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Take Trisolvat exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones while you are using this medicine.

Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Trisolvat.

Store at room temperature away from moisture, heat, and light.

Detailed Trisolvat dosage information


Often, no treatment is needed for an antibiotic overdose. Usually, you'll need to watch for stomach upset and possibly diarrhea. In those cases, you should give extra fluids.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Trisolvat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Trisolvat if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Trisolvat if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Trisolvat is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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Slowly progressive cystic leukoencephalopathy with megalencephaly in a Japanese boy. At 1 d, 3 d and 7 d, there was a highly significant difference in the number of NSCs between hypoxic and hypoxic-ischemic group. Bone quality was deteriorated and fragility was increased in rats 6 months after surgical menopause. The patient-related orbital volume showed a significant influence: a bi-quadratic analytical equation liking the osteotomy size, the orbital volume and the targeted eyeball protrusion has been established. The contribution of MetS to the prevalence of coronary heart disease (CHD) in different age-gender groups is currently unknown. Losses of 6q14.1-q27 and 17p13.3-q11.1 and gains of 19q13.12-q13.2 and 20q13.12-q13.33 were correlated with lymph vessel involvement. To evaluate the specificity and sensitivity of strip meniscometry (SM) testing in conjunction with tear function tests in the diagnosis of dry eye (DE) disease and to investigate the effect of SM on reflex tearing.

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Plasma salicylate levels after soluble and effervescent aspirin. The geography of graduate medical education: imbalances signal need for new distribution policies. Generally, the current GNA methods fall into global heuristic seed-and-extend approaches. Studies have shown that sleep shelters old verbal memories from associative interference arising from new, more recently acquired memories. People were asked about the age they expected to live and the health status they expected to have at ages 60, 70, 80 and 90, using the EQ-5D descriptive system.

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The integration of preventive medicine in health care in the Netherlands (1890-1940). Moreover, oxidative modifications of HDL found in patients with cardiovascular disease reduce the ability of apolipoproteins to remove cellular cholesterol by the ABCA1 pathway. A man in his thirties, previously healthy man had undergone elective knee arthroscopy with synovectomy. Metabolic syndrome is a cluster of metabolic disturbances including insulin resistance, dyslipidemia, hypertension, abdominal obesity and high blood sugar. To describe experiences, lessons and the implications related to the use of conferencing technology to support three drug policy research groups within a three-year period, using the action case research method.

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Postnatal development and behaviour was assessed on a wide-ranging battery of tests. Growth of human osteoblast-like cells on alkanethiol on gold self-assembled monolayers: the effect of surface chemistry. The molecular mechanisms for self-renewal, maintenance of pluripotency and lineage specification are poorly understood, but recent results point to a key role for epigenetic mechanisms. These results suggest that the medial temporal output is primarily organized hierarchically, but at the same time, it has multiple exits of information. This trend, already very familiar to high-income countries such as Canada, the United States of America and some European nations, takes on a special meaning stemi plavix dose in Africa, where several national HIV/AIDS laws make HIV transmission or exposure a crime. Action of gonadotropic hormones on the infantile testicle of young water turtles, Emys leprosa S. The preparation of a three-dimensionally (3D) ordered macroporous iron-platinum (FePt) film derived from monodisperse FePt nanoparticles (approximately 3 nm in diameter) and polystyrene latex particles (254 nm in diameter) is described. The results of this study indicate that the ALT/TGL ratio has a high sensitivity and specificity to identify NAFLD, suggesting that it could be a useful marker to recognize NAFLD in asymptomatic overweight and obese women. In such cultures, the proliferation of precursor cells, the formation of postmitotic cells, and, finally, the cytodifferentiation of neurons were observed. In parallel, the possibility that it may also be involved in the pathogenesis of stress-induced early embryonic death seems to emerge from studies, which addressed the embryotoxic potential of another cytokine, tumor necrosis factor-alpha (TNF-alpha).

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Somatic embryogenesis in leaves and leaf-derived protoplasts of Actinidia deliciosa var. Ptosis surgery, if required, was performed after the strabismus surgery. Bilateral dislocation of the hip in spina bifida: a long-term follow-up study. Lactation and neonatal nutrition: defining and refining the critical questions. These data indicate that (i) the blockage of the erythroblast differentiation by Spi-1 occurs independently of p53 alteration (ii) p53 alteration is not necessary to confer Epo independence and tumorigenicity to spi-1 transgenic proerythroblasts. Hospital acquired native valve endocarditis: analysis of 22 cases presenting over 11 years. An 87-year-old man diagnosed as having advanced gastric carcinoma was admitted to our hospital. The serology showed total bilirubin 10.6 mg/dL with direct bilirubin of 7.0 mg/dL.

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